Results 51 to 60 of about 9,000,286 (286)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Double-Branch Multi-Scale Contextual Network: A Model for Multi-Scale Street Tree Segmentation in High-Resolution Remote Sensing Images

open access: yesSensors
Street trees are of great importance to urban green spaces. Quick and accurate segmentation of street trees from high-resolution remote sensing images is of great significance in urban green space management. However, traditional segmentation methods can
Hongyang Zhang, Shuo Liu
doaj   +1 more source

MAAUNet: Exploration of U-shaped encoding and decoding structure for semantic segmentation of medical image

open access: yesJournal of Measurement Science and Instrumentation, 2022
In view of the problems of multi-scale changes of segmentation targets, noise interference, rough segmentation results and slow training process faced by medical image semantic segmentation, a multi-scale residual aggregation U-shaped attention network ...
SHAO Shuo, GE Hongwei
doaj  

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Multilevel Space-Time Aggregation for Bright Field Cell Microscopy Segmentation and Tracking

open access: yesInternational Journal of Biomedical Imaging, 2010
A multilevel aggregation method is applied to the problem of segmenting live cell bright field microscope images. The method employed is a variant of the so-called “Segmentation by Weighted Aggregation” technique, which itself is based on Algebraic ...
Tiffany Inglis   +6 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

R2KAN-U-Net: A Novel Architecture Integrating Kolmogorov–Arnold Networks with Residual U-Net for Robust Traffic Sign Segmentation

open access: yesSensors
Traffic sign segmentation is a fundamental component of intelligent transportation systems and autonomous driving, where reliable pixel-level perception is required under challenging real-world conditions such as illumination variations, occlusion, scale
Taha Ben-Abbou   +5 more
doaj   +1 more source

Segmentation of Thai handwritten text for automatic document retrieval [PDF]

open access: yes, 2008
There is a huge amount of documents in Thai government organizations. Although automatic document image retrieval systems in English have been proposed and developed, there are no specific system which is capable to retrieve relevant information from ...
Fung, C.C., Chamchong, R.
core  

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

On the axiomatic foundations of linear scale-space : Combining semi-group structure with causality vs. scale invariance

open access: yes, 1996
The notion of multi-scale representation is essential to many aspects of early visual processing. This article deals with the axiomatic formulation of the special type of multi-scale representation known as scale-space representation.
Lindeberg, Tony
core   +2 more sources

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