Results 31 to 40 of about 366,438 (285)

Multiscale Active Contours [PDF]

open access: yes, 2018
We propose a new multiscale image segmentation model, based on the active contour/snake model and the Polyakov action. The concept of scale, general issue in physics and signal processing, is introduced in the active contour model, which is a well-known ...
Bresson, Xavier   +2 more
core  

Scale-Space Autoencoders for Unsupervised Anomaly Segmentation in Brain MRI [PDF]

open access: yes, 2020
Brain pathologies can vary greatly in size and shape, ranging from few pixels (i.e. MS lesions) to large, space-occupying tumors. Recently proposed Autoencoder-based methods for unsupervised anomaly segmentation in brain MRI have shown promising performance, but face difficulties in modeling distributions with high fidelity, which is crucial for ...
Baur, Christoph   +3 more
openaire   +2 more sources

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

SBNet: Sparse Blocks Network for Fast Inference

open access: yes, 2018
Conventional deep convolutional neural networks (CNNs) apply convolution operators uniformly in space across all feature maps for hundreds of layers - this incurs a high computational cost for real-time applications.
Pokrovsky, Andrei   +3 more
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

MambaMeshSeg-Net: A Large-Scale Urban Mesh Semantic Segmentation Method Using a State Space Model with a Hybrid Scanning Strategy

open access: yesRemote Sensing
Semantic segmentation of urban meshes plays an increasingly crucial role in the analysis and understanding of 3D environments. Most existing large-scale urban mesh semantic segmentation methods focus on integrating multi-scale local features but struggle
Wenjie Zi   +3 more
doaj   +1 more source

Fast determination of coarse grained cell anisotropy and size in epithelial tissue images using Fourier transform

open access: yes, 2019
Mechanical strain and stress play a major role in biological processes such as wound healing or morphogenesis. To assess this role quantitatively, fixed or live images of tissues are acquired at a cellular precision in large fields of views.
Delanoë-Ayari, H.   +5 more
core   +1 more source

Coarse-to-Fine Segmentation with Shape-Tailored Continuum Scale Spaces [PDF]

open access: yes2017 IEEE Conference on Computer Vision and Pattern Recognition (CVPR), 2017
We formulate an energy for segmentation that is designed to have preference for segmenting the coarse over fine structure of the image, without smoothing across boundaries of regions. The energy is formulated by integrating a continuum of scales from a scale space computed from the heat equation within regions.
Naeemullah Khan   +3 more
openaire   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

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