Results 91 to 100 of about 11,865,109 (300)
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates
FEBS Letters, EarlyView.Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino +2 more
wiley +1 more source
, 2023 This project compared a SCALE-UP teaching model to a traditional teaching model. Traditional teaching is now considered a poor motivator for student performance and interests, and the SCALE-UP model was proposed to combat these problems.
NC DOCKS at East Carolina University +1 more
core
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
, 2015 Reactor performance of confined jet mixers for continuous hydrothermal flow synthesis of nanomaterials is investigated for the purpose of scale-up from laboratory scale to pilot-plant scale.
Zhang, Yang +7 more
core +1 more source
Scale‐up of the cross‐flow flat‐plate airlift photobioreactor
, 2020 To commercialize large‐scale and high‐density microalgae cultivation, a 10L cross‐flow flat‐plate airlift photobioreactor (CFA‐PBR) was designed and amplified to two types of 40L CFA‐PBRs via different scaling‐up methods.
Luhaibo Zhao +7 more
core +1 more source
JAHRSummary of evidence from collaboration on Regional Innovation in AI for Creative Industries undertaken by Creative Manchester, Digital Futures and Turing Innovation ...
Ettah, Effa-Bassey +2 more
+5 more sources
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
From start-up to scale-up: examining public policies for the financing of high-growth ventures. Bruegel Working Paper 04 / 2017 [PDF]
, 2016 We examine the challenge entrepreneurial companies face in going beyond the start-up phase and growing into large successful companies. We examine the long-term financing of these so-called scale-up companies, focusing on the United States, Europe ...
Duruflé, Gilles +10 more
core +1 more source