Results 91 to 100 of about 23,299,567 (273)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Deterministic Scale-Free Networks

, 2001
Scale-free networks are abundant in nature and society, describing such diverse systems as the world wide web, the web of human sexual contacts, or the chemical network of a cell.
Albert, Albert, Albert, Albert-László Barabási, Amaral, Barabási, Barabási, Barabási, Broder, Dorogovtsev, Dorogovtsev, Dorogovtsev, Dorogovtsev, Erzsébet Ravasz, Faloutsos, Jeong, Jeong, Krapivsky, Krapivsky, Liljeros, Mandelbrot, Newman, Newman, Tamás Vicsek, Vicsek   +24 more
core   +2 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Controlled Shared Memory (COSM) Isolation: Design and Testbed Evaluation

IEEE Access
Recent memory-sharing approaches, e.g., based on the Compute Express Link (CXL) standard, allow the flexible high-speed sharing of data (i.e., data communication) among multiple hosts.
Vignesh Sundaravarathan, Martin Reisslein, Akhilesh S. Thyagaturu, Nick Ross, Gurpreet Singh Kalsi, Jason Howard, Jan Kaisrlik, Bartosz Matwiejczyk, Marek M. Landowski, Piotr Dorozynski, Harvey Vrsalovic, Sanjaya Tayal   +11 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

High-throughput computational stacking reveals emergent properties in natural van der Waals bilayers

Nature Communications
Stacking of two-dimensional (2D) materials has emerged as a facile strategy for realising exotic quantum states of matter and engineering electronic properties.
Sahar Pakdel, Asbjørn Rasmussen, Alireza Taghizadeh, Mads Kruse, Thomas Olsen, Kristian S. Thygesen   +5 more
doaj   +1 more source

The Extragalactic Distance Scale

, 1996
Cepheid variables are used to derive a Virgo cluster distance of 16.0 +/- 1.5 Mpc. In conjunction with the Coma velocity and the well-established Coma/Virgo distance ratio, this yields a Hubble paprameter Ho = 81 +/- 8 km/s/Mpc.
Bergh, Sidney van den
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Parametric Design of Continuum Robots Using Interlocking Ball Joints

Advanced Intelligent Systems
Continuum robots are promising systems for minimally invasive surgical procedures, enabling safe and dexterous access to deep regions in the human body.
Alexandre Mesot, Quentin Boehler, Florian Heemeyer, Sean Lyttle, Buse Aktaş, Bradley J. Nelson   +5 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source