Results 121 to 130 of about 23,299,567 (273)
In this paper, a parallel nonoverlapping and nonconformal domain decomposition method (DDM) is proposed for fast and accurate analysis of electrically large objects in the condition of limited resources.
Qin Su +6 more
doaj +1 more source
Entropy creation rate is introduced for a system interacting with thermostats ({\it i.e.}, in the usual language, for a system subject to internal conservative forces interacting with ``external'' thermostats via conservative forces) and a fluctuation ...
Evans D., G. Gallavotti, Gallavotti G.
core +1 more source
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Studies on Droplet Size Distribution of Oil-in-Water Emulsion in SMX Static Mixer
Oil droplet size distribution of an emulsion produced by Sulzer Chemtech's static SMX static mixer under flow condition was experimentally studied and reported. The dispersed phase of vegetable oil-in-water (O/W) emulsion produced through static mixer by
L. Muruganandam, D. Kunal, G. O. Melwyn
doaj
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
This is a mini-review on the mechanism of leptogenesis, with a special emphasis on low-scale leptogenesis models which are testable in foreseeable laboratory experiments at Energy and Intensity frontiers.
Dev, P. S. Bhupal
core +1 more source
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Lateral shifting of gold particles on a metal surface
Owing to the intricate interplay between light and matter, the scattering optical force has garnered considerable attention in scientific research. This force invariably propels particles along the trajectory of light propagation.
Yanan Fu +4 more
doaj +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source

