Results 81 to 90 of about 17,468,919 (335)

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Discrete Scale Relativity

open access: yes, 2007
The possibility that global discrete dilation invariance is a fundamental symmetry principle of nature is explored. If the discrete self-similarity observed in nature is exact, then the Principle of General Covariance needs to be broadened in order to ...
C.W. Misner   +4 more
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Clinical evaluation of a novel plasma pTau217 electrochemiluminescence immunoassay in Alzheimer’s disease

open access: yesScientific Reports
A growing literature suggests that plasma levels of tau phosphorylated at amino acid 217 (pTau217) performs similarly to cerebrospinal fluid (CSF) biomarkers and PET imaging to detect amyloid pathology and to provide diagnostic and prognostic information
Pia Kivisäkk   +10 more
doaj   +1 more source

Scale matters [PDF]

open access: yesPhilosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, 2018
The applicability of Navier–Stokes equations is limited to near-equilibrium flows in which the gradients of density, velocity and energy are small. Here I propose an extension of the Chapman–Enskog approximation in which the velocity probability distribution function (PDF) is averaged in the coordinate phase space as well as the velocity phase space. I
openaire   +2 more sources

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Scaling Up, Scaling Down

open access: yesA Peer-Reviewed Journal About, 2023
This article explores the shifting perceptual scales of racial epistemology and anti-blackness in predictive policing technology. Following Paul Gilroy, I argue that the historical production of racism and anti-blackness has always been deeply entwined with questions of scale and perception. Where racialisation was once bound to the anatomical scale of
openaire   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

open access: yesFEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino   +7 more
wiley   +1 more source

Controlled Shared Memory (COSM) Isolation: Design and Testbed Evaluation

open access: yesIEEE Access
Recent memory-sharing approaches, e.g., based on the Compute Express Link (CXL) standard, allow the flexible high-speed sharing of data (i.e., data communication) among multiple hosts.
Vignesh Sundaravarathan   +11 more
doaj   +1 more source

Enhancement of small-scale turbulent dynamo by large-scale shear

open access: yes, 2017
Small-scale dynamos are ubiquitous in a broad range of turbulent flows with large-scale shear, ranging from solar and galactic magnetism to accretion disks, cosmology and structure formation.
Brandenburg, Axel   +2 more
core   +1 more source

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