Results 91 to 100 of about 8,690,693 (300)

Adaptive Computing for Scale-Up Problems

Computing in Science & Engineering
Adaptive Computing is an application-agnostic outer loop framework to strategically deploy simulations and experiments to guide decision making for scale-up analysis. Resources are allocated over successive batches, which makes the allocation adaptive to some objective such as optimization or model training.
Kevin Patrick Griffin, Hilary Egan, Marc T. Henry de Frahan, Juliane Mueller 0002, Deepthi Vaidhynathan, Dylan Wald, Rohit Chintala, Olga A. Doronina, Hariswaran Sitaraman, Ethan Young, Ryan N. King, Jibonananda Sanyal, Marc Day, Ross E. Larsen   +13 more
openaire   +2 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Adaptation of the Professional Moral Courage Scale to Turkish Culture: A Validity and Reliability Study

International Journal of Turkish Education Sciences
In this study, it was aimed to adapt the "Professional Moral Courage" scale developed by Sekerka et al. (2009) to Turkish culture to assess teachers' Professional Moral Courage levels.
Sami Yollu, Hanifi Yumuşak, Mehmet Korkmaz   +2 more
doaj   +1 more source

Studying adaptation at the invisible scale

Proceedings of the National Academy of Sciences
In order to understand adaptation by natural selection, it is necessary to observe organisms in their natural habitat. For this reason, the field of behavioral ecology, which specializes in testing adaptive explanations for biological observations, is dominated by research on larger multicellular animals such as insects, mammals ...
Griffin, AS, West, SA
openaire   +2 more sources

Local methods with adaptivity via scaling

Russian Mathematical Surveys
The rapid development of machine learning and deep learning has introduced increasingly complex optimization challenges that must be addressed. Indeed, training modern, advanced models has become difficult to implement without leveraging multiple computing nodes in a distributed environment.
Saveliy Chezhegov, Sergey Skorik, Nikolas Khachaturov, Danil Shalagin, Aram Avetisyan, Aleksandr Beznosikov, Martin Takác 0001, Yaroslav Kholodov, Alexander V. Gasnikov   +8 more
openaire   +2 more sources

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Understanding the clinical profile of Continuous Traumatic Stress Responses: insights from the adaptation of the Continuous Traumatic Stress Response Scale (CTSR) in Ukrainian military personnel

European Journal of Psychotraumatology
Background: Despite ongoing debate on the necessity of using the Continuous Traumatic Stress Response (CTSR) concept in contexts of repetitive threat – where the traditional post-traumatic stress disorder (PTSD) paradigm is insufficient [Goral, A., Feder-
Oleksandr Avramchuk, Maryana Mykolaychuk, Tetiana Zavada, Volodymyr Demydiuk, Aviva Goral, Oksana Senyk   +5 more
doaj   +1 more source

Örgütsel Hafıza Ölçeği’nin Türkçe’ye Uyarlanması: Geçerlik ve Güvenirlik Çalışması

Sakarya University Journal of Education, 2016
Bu çalışmanın amacı İngilizce Örgütsel Hafıza Ölçeği’ni (Dunham, 2010) Türkçe’ye uyarlamaktır. Ölçeğin dil geçerliği çeviri tekrar-çeviri ve İngilizce ve Türkçe formlar arasında Pearson korelasyon katsayısının hesaplanması yöntemleri ile test edilmiştir.
İbrahim Limon
doaj   +1 more source

Turkish Adaptation of the Family Adaptability and Cohesion Scale IV

International Journal of Assessment Tools in Education, 2018
The aim of this study was to examine the psychometric properties of the Turkish version of Family Adaptability and Cohesion Scale IV (FACES IV) Questionnaire Package, and also to achieve a valid and reliable assessment tool for the further investigations of the Circumplex Model of Marital and Family Systems in Turkish culture.
Türkdoğan, Turgut, Duru, Erdinç, Balkıs, Murat   +2 more
openaire   +6 more sources

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source