Results 101 to 110 of about 503,141 (263)

Application of Scale-adaptive Dust Emission Scheme to CMA-CUACE/Dust

open access: yes应用气象学报
Sand and dust storms are significant natural disasters which affect East Asia and China in spring, occurring from March to May. Performances of CMA-CUACE/Dust, an operational Asian sand and dust storm numerical forecasting system of CMA since 2006, are ...
Zhou Chunhong   +8 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Classifier-Free Guidance with Adaptive Scaling

open access: yes
Classifier-free guidance (CFG) is an essential mechanism in contemporary text-driven diffusion models. In practice, in controlling the impact of guidance we can see the trade-off between the quality of the generated images and correspondence to the prompt.
Malarz, Dawid   +4 more
openaire   +3 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Beş Faktörlü Başarı Hedef Yönelim Ölçeğinin Fen Bilimleri Dersi İçin Türkçe’ye Uyarlanması

open access: yesAnadolu Üniversitesi Eğitim Fakültesi dergisi
Bu çalışmanın amacı Lüftenegger, Bardach, Bergsmann, Schober ve Spiel (2019) tarafından geliştirilen performans hedefin hem normatif hem de görünürlük özelliğini yaklaşım ve kaçınma çerçevesinde ele alan 5 faktörlü Başarı Hedef Yönelim Ölçeği’ni Fen ...
Murat Akyıldız   +2 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

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