Results 61 to 70 of about 1,443 (288)

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Operator product expansion of inflationary correlators and conformal symmetry of de Sitter

open access: yes, 2012
We study the multifield inflationary models where the cosmological perturbation is sourced by light scalar fields other than the inflaton. The corresponding perturbations are both scale invariant and special conformally invariant. We exploit the operator
Riotto, A   +3 more
core   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

Spinors, embeddings and gravity

open access: yes, 1988
This thesis is concerned with the theory of spinors, embeddings and everywhere invariance with applications to general relativity. The approach is entirely geometric with particular emphasis on the use of natural structures.
Swift, S.T, Swift, Simon
core   +1 more source

Universal fine grained asymptotics of free and weakly coupled quantum field theory

open access: yesJournal of High Energy Physics
We give a rigorous proof that in any free quantum field theory with a finite group global symmetry G, on a compact spatial manifold, at sufficiently high energy, the density of states ρ α (E) for each irreducible representation α of G obeys a universal ...
Weiguang Cao, Tom Melia, Sridip Pal
doaj   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

open access: yesFEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer   +7 more
wiley   +1 more source

Duality defects in D n -type Niemeier lattice CFTs

open access: yesJournal of High Energy Physics
We discuss the construction of duality defects in c = 24 meromorphic CFTs that correspond to Niemeier lattices. We will illustrate our constructions for the D n -type lattices.
Sachin Grover   +2 more
doaj   +1 more source

Renormalization group flows between Gaussian fixed points

open access: yesJournal of High Energy Physics, 2022
A scalar theory can have many Gaussian (free) fixed points, corresponding to Lagrangians of the form ϕ□ n ϕ. We use the non-perturbative RG to study examples of flows between such fixed points. We show that the anomalous dimension changes continuously in
Diego Buccio, Roberto Percacci
doaj   +1 more source

Conformal invariance in two-dimensional turbulence

open access: yes, 2006
10 pages, 5 figures, 1 tableSimplicity of fundamental physical laws manifests itself in fundamental symmetries. While systems with an infinity of strongly interacting degrees of freedom (in particle physics and critical phenomena) are hard to describe ...
Boffetta, G.   +8 more
core   +1 more source

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