Results 141 to 150 of about 9,009,506 (353)

Information Flow Structure in Large-Scale Product Development Organizational Networks [PDF]

In recent years, understanding the structure and function of complex networks has become the foundation for explaining many different real- world complex social, information, biological and technological phenomena.
Dan Braha, Yaneer Bar-Yam
core  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Development and validation of the Chinese school environment influencing physical activity habits scale

Frontiers in Education
IntroductionRegular physical activity is essential for preventing overweight and obesity in children and adolescents while also enhancing mental well-being.
Shengting Dai, Shengting Dai, Yang Wu, Yang Wu, Jingfei Yan, Jingfei Yan, Li Zeng, Li Zeng   +7 more
doaj   +1 more source

Development of Perception of Child Maltreatment Scale [PDF]

, 2013
Sunday B. Fakunmoju, Funmi O. Bammeke
openalex   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

The Development and Testing of an Assessment Scale for Insufficiencies in Family Resilience

Nursing Reports
Background and purpose: When a family becomes aware of family symptoms, family resilience is defined as its power to autonomously and actively improve its own family functions.
Naohiro Hohashi, Natsumi Kijima
doaj   +1 more source

Project on Human Development in Chicago Neighborhoods (PHDCN): Physical Development Scale, Wave 2, 1997-2000

, 1997
Felton J. Earls, Jeanne Brooks‐Gunn, Stephen W. Raudenbush, Robert J. Sampson   +3 more
openalex   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Development of the 0-6 Years Old Psychosocial Development Attitudes Scale and the First Application of the Scale Through Educational Intervention

Journal of Nursology, 2022
Ayşegül DÖNMEZ , Esra ENGİN, Gülseren KESKİN, Zehra BAYKAL AKMEŞE, Tuğba DURMUŞ   +4 more
doaj   +1 more source