Results 131 to 140 of about 3,504,743 (313)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Quality of Parenting Programs and Child Development Outcomes: The Case of Peru\u27s Cuna Mas
, 2018 This paper analyzes the association between quality of parenting programs and child development outcomes. It focuses on parenting programs delivered through home visits (i.e., home visiting programs) in which a paraprofessional works with the caregiver ...
Inter-American Development Bank
core +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
President\u27s Report 2024 Executive Summary
From Resolutions to Solutions: A Year of Transformation. President Ilan Goldfajn\u27s second year at the IDB began with the most consequential annual meetings in over a decade.
Inter-American Development Bank
core +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
The development of Anthropocene Awareness Scale
PLOS ONEThe political influence of the Anthropocene concept stems from its analytic potential to encompass various disciplines and capture public attention. However, there is a lack of research examining the extent to which the public has adopted the views embodied in the Anthropocene. We developed a scale to measure awareness of the Anthropocene.
Donghun Kang, Moon Choi
openaire +3 more sources
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Konuşma Becerisi Öz Yeterlilik İnancı Ölçeği: Bir Ölçek Geliştirme Çalışması
Ana Dili Eğitimi Dergisiİlkokul düzeyinde verilen konuşma eğitimi, öğrencilerin dil ve etkili iletişim becerilerinin temellerinin atıldığı kritik bir gelişim sürecini temsil etmektedir.
Ayşegül Mazı, Banu Aktürkoğlu
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source