Results 111 to 120 of about 3,504,743 (313)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Supporting National Development Banks to Drive Investment in the Nationally Determined Contributions of Brazil, Mexico, and Chile [PDF]
, 2017 The Paris Agreement combats climate change through country-defined sustainable development plans, aiming to align financing flows with low-carbon climate resilient growth.
Inter-American Development Bank
core +1 more source
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Mi Tienda\u27s Innovative Rural Supply Network
, 2010 Small, family-run grocery stores, known as tiendas de abarrotes, are essential for supplying basic goods and services in thousands of low-income rural communities in Mexico.These stores are convenient -many are open 24 hours a day -but they normally ...
Inter-American Development Bank
core +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Healthy Lifestyle Scale (Helis): A Scale Development Research
SDÜ Vizyoner DergisiThe purpose of the study is to create a viable and trustworthy instrument for evaluating people's attitudes and actions on leading healthy lives. This methodological and psychometric study is conducted with 760 individuals who agreed to participate in ...
Durmuş Gökkaya
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Prediction of TBM penetration rate for different surrounding rocks and cutter head diameters
HeliyonThe penetration rate (PR) of tunnel boring machines (TBMs) is often used to evaluate tunneling performance and predict construction period costs. However, most penetration rate (PR) prediction models are based on a single specific project, which leads to
Yang Yalei +4 more
doaj +1 more source
10181 Executive Summary – Program Development for Extreme-Scale Computing [PDF]
, 2010 From May 2nd to May 7th, 2010, the Dagstuhl Seminar 10181 ``Program Development for Extreme-Scale Computing '' was held in Schloss Dagstuhl~--~Leibniz Center for Informatics.
Schulz, Martin +3 more
core +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source