Results 91 to 100 of about 9,009,506 (353)

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Mothers’ Perceptions and Attitudes Toward Human Milk Banking Scale: A Scale Development Study

open access: yesJournal of Behçet Uz Children's Hospital
Objective: The aim of this investigation is to construct and psychometrically evaluate a novel measurement instrument designed to capture maternal perceptions and attitudes regarding donor milk services.
Şeyma Kilci Erciyas   +3 more
doaj   +1 more source

Labor Relations Conflict in the Workplace: Scale Development, Consequences and Solutions [PDF]

open access: yes, 2017
Because the goals of employers and employees are often incompatible, conflicts are inevitable and an essential part of organizational life. The three studies reported in this paper addressed the issues of identifying the dimensions of workplace conflicts
Xi, Meng   +3 more
core   +1 more source

The Geologic Time Scale: The Development of Life through time [PDF]

open access: yes
This text assists in understanding time relationships and how life on Earth has changed over time. The dates shown were compiled from several available sources.

core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

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