Results 71 to 80 of about 3,504,743 (313)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
, 2023 Spanish version available in IDRC Digital Library : Open course collection TPD at scale and innovation in teacher professional development (Spanish version)The goal of TPD@Scale is quality education for all through empowered and effective teachers.
Coalición para el Sur Global DPD@Escala (TPD@Scale)
core
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The Molecular Mechanism of Craniofacial Cartilage Deformity Induced by High Glucose in Zebrafish
Current Issues in Molecular BiologyGestational diabetes mellitus (GDM), a prevalent metabolic disorder in pregnancy, induces maternal hyperglycemia and elevates fetal malformation risks, particularly in craniofacial development.
Xiaomei Chen +4 more
doaj +1 more source
Inter-American Development Bank Annual Report 2008: The Year in Review
, 2009 This Annual Report 2008: A Year in Review contains a review of the Bank\u27s operations in 2008, loans, guarantees and grants, and in a separate volume, Management\u27s Discussion and Analysis: Ordinary Capital; the financial statements of the Bank; and ...
Inter-American Development Bank
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Venture Capital for Low-Income Markets [PDF]
, 2010 Investing in housing, healthcare, education, basic utilities and nutrition can not only fulfill a social mission, but it can also be a profitable business venture.This is the concept of IGNIA Fund, which will channel venture capital resources to fund ...
Inter-American Development Bank
core +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Crystallinity-Controlled Atomic Layer Deposition of Ti-Doped ZrO2 Thin Films
ECS AdvancesWe investigated Ti-doped ZrO _2 deposition using a cyclopentadienyl tris(dimethylamino) zirconium (CpZr(NMe _2 ) _3 ) precursor and a titanium tetraisopropoxide (TTIP) precursor using an O _3 thermal atomic layer deposition process.
Seokhwi Song +7 more
doaj +1 more source