Results 61 to 70 of about 9,009,506 (353)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

The Molecular Mechanism of Craniofacial Cartilage Deformity Induced by High Glucose in Zebrafish

Current Issues in Molecular Biology
Gestational diabetes mellitus (GDM), a prevalent metabolic disorder in pregnancy, induces maternal hyperglycemia and elevates fetal malformation risks, particularly in craniofacial development.
Xiaomei Chen, Yong Huang, Xin Yang, Huiqiang Lu, Jian Yang   +4 more
doaj   +1 more source

Development of Sport Courage Scale [PDF]

Journal of Human Kinetics, 2012
Development of Sport Courage Scale While theory and practice of sport have much to say about fear, stress and anxiety, they have little to say about courage. Therefore, the purpose of this study was to develop a Sport Courage Scale. Data were collected from two groups of male and female athletes aged from 13 to 22 in different individual
KONTER, ERKUT, Ng, Johan
openaire   +3 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Attitudes towards anorexia nervosa: Volitional stigma differences in a sample of pre-clinical medicine and psychology students [PDF]

, 2016
Background: Anorexia nervosa (AN) is a highly stigmatised condition, with treatment often involving multidisciplinary care. As such, understanding and comparing the attitudes of emerging mental health and medical professionals towards AN, within the ...
Bannatyne, Amy Jean, Stapleton, Peta Berenice   +1 more
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Crystallinity-Controlled Atomic Layer Deposition of Ti-Doped ZrO2 Thin Films

ECS Advances
We investigated Ti-doped ZrO _2 deposition using a cyclopentadienyl tris(dimethylamino) zirconium (CpZr(NMe _2 ) _3 ) precursor and a titanium tetraisopropoxide (TTIP) precursor using an O _3 thermal atomic layer deposition process.
Seokhwi Song, Eungju Kim, Kyunghoo Kim, Jangho Bae, Jinho Lee, Chang Hwa Jung, Hanjin Lim, Hyeongtag Jeon   +7 more
doaj   +1 more source

Evaluating teachers' and trainers' development in a large scale curriculum development project in South Yorkshire [PDF]

, 2004
The evaluative research upon which the paper is based focuses on the first three years of a six-year project “Pathways to Success” (PW) currently taking place in South Yorkshire and funded by the European Social Fund (ESF) as part of the Objective 1 ...
Coldwell, M. R., Holland, M. R., Rybinski, D., Trickey, S.   +3 more
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Impacts of large scale development: does space make a difference? [PDF]

, 2005
Large scale development, a process to rapidly transform urban built environment since the industrial modernism, has been often criticized for creating fragmented environments that impair urban vitality.
Yang, Tao
core