Results 231 to 240 of about 8,984,201 (303)

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Impact of a brief diabetes education on teachers' diabetes-related knowledge, attitude, and confidence: a nonrandomized school-based intervention study. [PDF]

Front Public Health
Horváth MD, Tesch Z, Buzás N, Papp-Zipernovszky O.   +3 more
europepmc   +1 more source

Amyloid-beta-targeting monoclonal antibodies for people with mild cognitive impairment or mild dementia due to Alzheimer's disease. [PDF]

Cochrane Database Syst Rev
Nonino F, Minozzi S, Sambati L, Del Giovane C, Baldin E, Bassi MC, De Santis C, Gonzalez-Lorenzo M, Vignatelli L, Filippini G, Richard E.   +10 more
europepmc   +1 more source

Spirituality and Harmful or Hazardous Alcohol and Other Drug Use: A Meta-Analysis of Longitudinal Studies.

JAMA Psychiatry
Koh HK, Frederick DE, Balboni TA, O'Reilly SM, Kelly JF, Humphreys K, Botticelli M, Mathur MB, Psimopoulos CS, Long KNG, VanderWeele TJ.   +10 more
europepmc   +1 more source