Results 61 to 70 of about 81,520 (219)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
The effective Planck mass and the scale of inflation [PDF]
The European Physical Journal C, 2015 9 pages + 3 appendices, 4 figures. References added, distinction between the strength of gravity and strong coupling scale emphasized.
Antoniadis, Ignatios, Patil, Subodh P.
openaire +3 more sources
ISPRS International Journal of Geo-InformationTopographic scale characteristics contain valuable information for interpreting landform structures, which is crucial for understanding the spatial differentiation of landforms across large areas.
Xi Nan +3 more
doaj +1 more source
Frontiers in Earth Science, 2023 Floods pose a significant threat to the safety of countries with severe societal, economic, and environmental consequences, especially the flash floods in mountainous regions.
Tianxue Yu +5 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Planck scale effects in neutrino physics [PDF]
Physical Review D, 1993 24 pages, 1 figure (not included but available upon request), LaTex, IC/92/196, SISSA-140/92/EP, LMU-09 ...
AKHMEDOV E. +3 more
openaire +4 more sources
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Numerical Study of the Scale Effect on Flow Around a Propeller Using the CFD Method
Polish Maritime ResearchThis paper presents an investigation of the scale effect on the flow around a propeller using the CFD method. The differences in the numerical setup and the results obtained for the characteristics of an open water propeller are described and analysed in
Van-Vu Huynh +4 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source