Results 91 to 100 of about 3,865,865 (314)

Examination on level of scale efficiency in public hospitals in Tanzania. [PDF]

open access: yesCost Eff Resour Alloc, 2021
Fumbwe F   +4 more
europepmc   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Scaling Efficient LLMs

open access: yes
Recent LLMs have hundreds of billions of parameters consuming vast resources. Furthermore, the so called "AI scaling law" for transformers suggests that the number of parameters must scale linearly with the size of the data. In response, we inquire into efficient LLMs, i.e.
openaire   +2 more sources

Efficiency and Economies of Scale of Large Canadian Banks [PDF]

open access: yes
The authors measure the economies of scale of Canada's six largest banks and their cost-efficiency over time. Using a unique panel data set from 1983 to 2003, they estimate pooled translog cost functions and derive measures of relative efficiency and ...
Jason Allen, Ying Liu
core  

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Efficiency and Productivity in the Spanish Food Distribution Sector [PDF]

open access: yes
This study investigated the efficiency and productivity change of a sample of food distribution units (MERCAs) in Spain over the 1.997-1.999 period, applying non-parametric frontier methodology in a sales efficiency framework.
Palomares, Rafaela Dios
core   +1 more source

Analysing the efficiency of Portuguese pension funds : a stochastic frontier model [PDF]

open access: yes, 2007
This paper examines technical efficiency of Portuguese pension funds management companies, using a stochastic frontier model in order to obtain estimates of economies of scale and scope.
Barros, Carlos Pestana   +2 more
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

SNIPER: Efficient Multi-Scale Training

open access: yes, 2018
Presented at the NIPS 2018 ...
Singh, Bharat   +2 more
openaire   +2 more sources

Does size matter? : Economies of scale in the German mutual fund industry [PDF]

open access: yes, 2009
In this paper, we analyze economies of scale for German mutual fund complexes. Using 2002-2005 data of 41 investment management companies, we specify a hedonic translog cost function. Applying a fixed effects regression on a one-way error component model
Maurer, Raimond, Schaefer, Alexander
core  

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