Results 91 to 100 of about 1,091,788 (268)
The Efficiency of China’s Carbon Trading Schemes: A Tale of Seven Pilot Markets
CommoditiesThis study evaluates the efficiency of China’s seven emission trading schemes (ETS) piloted in 2013. We evaluate seven pilots’ overall technical and scale efficiencies and temporal dynamics during 2014–2023. We use a bootstrap correction data envelopment
Yigang Wei +3 more
doaj +1 more source
Scaling Inference-Efficient Language Models
CoRR21 pages, 18 figures, ICML ...
Song Bian 0002 +2 more
openaire +3 more sources
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Examining the Effect of Capital Structure and Financing on the Technical Efficiency of Pharmaceutical Companies Listed on the Stock Exchange [PDF]
حسابداری سلامت, 2013 Introduction: Choosing an optimal capital structure is prerequisite for maximizing the firm value. Given the competitive market conditions, determining the appropriate method of financing companies is boost for increasing their efficiency and viability ...
I. Dadashi +3 more
doaj
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Efficient Scaling of Bayesian Neural Networks
IEEE AccessWhile Bayesian neural networks (BNNs) have gained popularity for their theoretical guarantees and robustness, they have yet to see a convincing implementation at scale. This study investigates a variational inference-based neural architecture called Variational Density Propagation (VDP) that boasts noise robustness, self-compression and improved ...
Jacob R. Epifano +3 more
openaire +2 more sources
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Beyond Efficiency: Scaling AI Sustainably
IEEE MicroBarroso's seminal contributions in energy-proportional warehouse-scale computing launched an era where modern datacenters have become more energy efficient and cost effective than ever before. At the same time, modern AI applications have driven ever-increasing demands in computing, highlighting the importance of optimizing efficiency across the entire
Carole-Jean Wu +3 more
openaire +2 more sources
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source