Results 111 to 120 of about 3,865,865 (314)

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Cost Efficiency, Scale Elasticity and Scale Economies in Arab Banking

Banks and Bank Systems, 2006
This study investigates Cost Efficiency, Scale Elasticity and Scale Economies of the Jordanian, Egyptian, Saudi Arabian and Bahraini banking systems. Our sample comprises information on 82 banks operating in the countries under study over 1992-2000. The stochastic frontier and Fourierflexible form are used to estimate cost efficiency, scale elasticity ...
Al-Jarrah, I., Molyneux, Ph.
openaire   +2 more sources

Efficient Large Scale Video Classification

, 2015
Video classification has advanced tremendously over the recent years. A large part of the improvements in video classification had to do with the work done by the image classification community and the use of deep convolutional networks (CNNs) which produce competitive results with hand- crafted motion features. These networks were adapted to use video
Varadarajan, Balakrishnan, Toderici, George, Vijayanarasimhan, Sudheendra, Natsev, Apostol   +3 more
openaire   +2 more sources

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

The intermediate role of farmland transfer in the impact of digital financial inclusion on agricultural total factor productivity in China

Frontiers in Sustainable Food Systems
IntroductionEnhancing agricultural productivity and promoting sustainable development in China are critical priorities, given their significant contribution to food security and rural development.
Jiali Yang, Jiali Yang, Abate Meseretchanie   +2 more
doaj   +1 more source

Beyond Efficiency: Scaling AI Sustainably

IEEE Micro
Barroso's seminal contributions in energy-proportional warehouse-scale computing launched an era where modern datacenters have become more energy efficient and cost effective than ever before. At the same time, modern AI applications have driven ever-increasing demands in computing, highlighting the importance of optimizing efficiency across the entire
Carole-Jean Wu, Bilge Acun, Ramya Raghavendra, Kim Hazelwood   +3 more
openaire   +2 more sources

The Optimal Size of German Cities An Efficiency Analysis Perspective [PDF]

This work investigates the interrelation between production efficiency and population size of German cities. The productive efficiency in this context is the scale efficiency, which is a result of positive and negative agglomeration externalities.
Hitzschke, Stephan
core  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Technical and scale efficiency of cassava production system in Delta State, Nigeria: an application of Two-Stage DEA approach

Journal of Agriculture and Rural Development in the Tropics and Subtropics, 2015
The present study examines the level of pure technical and scale efficiencies of cassava production system including its sub-processes (that is production and processing stages) of 278 cassava farmers/processors from three regions of Delta State, Nigeria
Sanzidur Rahman, Brodrick O. Awerije
doaj