Results 131 to 140 of about 9,265,491 (302)

The Physics of Efficiency and Scaling

open access: yes
To understand whether a system can scale without scaling inputs, one must first distinguish between efficiency (optimizing the ratio of output to input) and scalability (the capacity to handle increased magnitude). 
openaire   +2 more sources

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Estimates of scale and cost efficiency for Federal Reserve currency operations [PDF]

open access: yes
Meeting the currency demands of depository institutions, businesses, and consumers costs the Federal Reserve more than half a billion dollars each year, yet, very little research has been devoted to understanding what factors affect such costs.
Diana Hancock, James Bohn, Paul Bauer
core  

Efficiency of Public Sector District Hospitals of India: A Data-envelopment Analysis

open access: yesIndian Journal of Public Health
Background: District hospitals are integral part of India’s public healthcare delivery system, yet national-level assessment of their efficiency is lacking.
Aarti Goyal   +2 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

SPATIAL VARIATIONS IN TECHNICAL EFFICIENCY AND RETURN TO SCALE IN THE INDONESIAN ECONOMY [PDF]

open access: yes, 2016
This paper reports an analysis of technical efficiency and returns to scale in the Indonesia economy during 1983-2013 with special attention to the spatial dimension of the economy.
Muchdie, Muchdie
core  

The effect of work accidents on the efficiency of production in the coal sector

open access: yesSouth African Journal of Science, 2011
In comparison with other sectors, mining is one of the sectors with the highest rates of work accidents. Such accidents negatively affect a country's economy by wasting domestic resources and causing losses of both labour force and working days.
Ya şar Kasap
doaj  

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Technical Efficiency of Indonesian Commercial Banks: An Application of Two-Stage DEA

open access: yesJurnal Manajemen dan Wirausaha, 2011
This paper uses data envelopment analysis (DEA) to investigate the technical efficiency of the Indonesian commercial banks over the period 2004-2009 using intermediation approach.
Tessa Vanina Soetanto, Ricky .
doaj  

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