Results 81 to 90 of about 19,400,250 (311)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Current status and applications of genome-scale metabolic models

open access: yesGenome Biology, 2019
Genome-scale metabolic models (GEMs) computationally describe gene-protein-reaction associations for entire metabolic genes in an organism, and can be simulated to predict metabolic fluxes for various systems-level metabolic studies.
Changdai Gu   +4 more
semanticscholar   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Escala de Funcionamiento Ejecutivo para Escolares: Análisis de las Propiedades Psicométricas

open access: yesPsicología Educativa: Revista de los Psicólogos de la Educación, 2019
Este trabajo presenta las propiedades psicométricas y un estudio de validación inicial de la Escala de Funcionamiento Ejecutivo para niños (EFE), la cual permite valorar la percepción de padres y docentes acerca de la frecuencia de ciertas conductas que ...
Celina Korzeniowski, Mirta Ison
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Chip-scale reconfigurable carbon nanotube physical unclonable functions

open access: yesNature Communications
With the rapid advancement of edge intelligence, ensuring the security of edge devices and protecting their communication has become critical. Physical unclonable functions, known as hardware fingerprints, are an emerging hardware security solution ...
Yang Liu   +10 more
doaj   +1 more source

Scale invariant distribution functions in quantum systems with few degrees of freedom

open access: yesSciPost Physics, 2018
Scale invariance usually occurs in extended systems where correlation functions decay algebraically in space and/or time. Here we introduce a new type of scale invariance, occurring in the distribution functions of physical observables. At equilibrium
Emanuele G. Dalla Torre
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Scale dependence of genome-derived microbial functional diversity informing soil functions

open access: yesGeoderma
The relationship between soil multifunctionality and microbial diversity is well established, and using genomic data to link microbial diversity with soil functions is increasingly recognized as a reliable approach, despite challenges such as horizontal ...
Nannan Wang   +10 more
doaj   +1 more source

Hermite-Hadamard Type Inequalities for the Class of Convex Functions on Time Scale

open access: yesMathematics, 2019
We investigate a time scale version of two auxiliary functions for the class of convex functions. We derive several novel dynamic inequalities for these classes of convex functions.
Saima Rashid   +4 more
doaj   +1 more source

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