Results 91 to 100 of about 19,866,917 (354)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Current status and applications of genome-scale metabolic models

Genome Biology, 2019
Genome-scale metabolic models (GEMs) computationally describe gene-protein-reaction associations for entire metabolic genes in an organism, and can be simulated to predict metabolic fluxes for various systems-level metabolic studies.
Changdai Gu, Gi Bae Kim, W. Kim, H. Kim, S. Lee   +4 more
semanticscholar   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Assessing Landscape Functions with Broad-Scale Environmental Data: Insights Gained from a Prototype Development for Europe

, 2009
We examine the advantages and disadvantages of a methodological framework designed to analyze the poorly understood relationships between the ecosystem properties of large portions of land, and their capacities (stocks) to provide goods and services ...
Haines-Young, Roy, Potschin, M., Bolliger, Janine, Potschin, Marion, Kienast, F., Verburg, Peter H., Rudolf S. de Groot, Peter H. Verburg, Bolliger, J., Heller, Iris, Janine Bolliger, Marion Potschin, Felix Kienast, Iris Heller, de Groot, R.S., Dirk Wascher, Wascher, D., Haines-Young, R., Roy Haines-Young, Groot, R.S., de, Kienast, Felix, Wascher, Dirk, de Groot, Rudolf S., Verburg, P.H., Heller, I.   +24 more
core   +1 more source

An analysis of costs in institutions of higher education in England [PDF]

, 2008
Cost functions are estimated, using random effects and stochastic frontier methods, for English higher education institutions. The article advances on existing literature by employing finer disaggregation by subject, institution type and location, and by
Johnes, G, Johnes, Jill, Johnes, J, Thanassoulis, Emmanuel, Johnes, Geraint, Thanassoulis, E   +5 more
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Escala de Funcionamiento Ejecutivo para Escolares: Análisis de las Propiedades Psicométricas

Psicología Educativa: Revista de los Psicólogos de la Educación, 2019
Este trabajo presenta las propiedades psicométricas y un estudio de validación inicial de la Escala de Funcionamiento Ejecutivo para niños (EFE), la cual permite valorar la percepción de padres y docentes acerca de la frecuencia de ciertas conductas que ...
Celina Korzeniowski, Mirta Ison
doaj   +1 more source

Linear programming solutions and distance functions under a constant returns to scale technology [PDF]

This note generalizes analytical relationships among activity variables of DEA models previously derived by Boussemart, Briec and Leleu (2007). We relax the asumption of constant returns to scale by showing that the key results hold under a weaker ...
Walter Briec, Jean-Philippe Boussemart, Hervé Leleu   +2 more
core  

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Chip-scale reconfigurable carbon nanotube physical unclonable functions

Nature Communications
With the rapid advancement of edge intelligence, ensuring the security of edge devices and protecting their communication has become critical. Physical unclonable functions, known as hardware fingerprints, are an emerging hardware security solution ...
Yang Liu, Jingfang Pei, Yingyi Wen, Lekai Song, Songwei Liu, Pengyu Liu, Wenyu Cui, Zihan Liang, Teng Ma, Xiaolong Chen, Guohua Hu   +10 more
doaj   +1 more source