Results 81 to 90 of about 19,866,917 (354)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Aggregation on Finite Ordinal Scales by Scale Independent Functions [PDF]
Order, 2004 In this article, three types of scale-independent functions aggregating finite ordinal numerical scales are studied. These are (1) functions mapping \(n\) copies of a scale into the very scale, (2) functions mapping \(n\) copies of a scale into a scale, and (3) functions mapping \(n\) scales into a scale.
MARICHAL, Jean-Luc, Mesiar, Radko
openaire +3 more sources
Psychometric evaluation of the reminiscence functions scale in the Malay language for older adults
The Reminiscence Functions Scale (RFS) is a commonly used survey instrument to assess psychological well-being among older adults. The study aims to examine the validity and reliability of the RFS in the Malay language. The RFS was back-translated into
Amit, Noh +6 more
core +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Scaled Density Functional Theory Correlation Functionals [PDF]
The Journal of Physical Chemistry A, 2007 We show that a simple one-parameter scaling of the dynamical correlation energy estimated by the density functional theory (DFT) correlation functionals helps increase the overall accuracy for several local and nonlocal functionals. The approach taken here has been described as the "scaled dynamical correlation" (SDC) method [Ramachandran, J.
Mohammed M, Ghouri +2 more
openaire +2 more sources
Temperature response functions (G-functions) for single pile heat exchangers [PDF]
, 2013 Foundation piles used as heat exchangers as part of a ground energy system have the potential to reduce energy use and carbon dioxide emissions from new buildings. However, current design approaches for pile heat exchangers are based on methods developed
Loveridge, F.A. +3 more
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Speed Scaling with an Arbitrary Power Function [PDF]
ACM Transactions on Algorithms, 2009 This article initiates a theoretical investigation into online scheduling problems with speed scaling where the allowable speeds may be discrete, and the power function may be arbitrary, and develops algorithmic analysis techniques for this setting. We show that a natural algorithm, which uses Shortest Remaining Processing Time for scheduling and sets ...
Chan, HL, Bansal, N, Pruhs, K
openaire +6 more sources