Results 91 to 100 of about 1,432,052 (301)

Chain architectures of various cellulose-based antiscalants on the inhibition of calcium carbonate scale

Scientific Reports, 2020
Two series of cellulose-based antiscalants with different chain architectures, i.e., linear carboxymethyl cellulose (CMC) and branch-shaped carboxymethyl cellulose-graft-poly(acrylic acid) (CMC-g-PAA), were synthesized.
Wei Yu, Hu Yang
doaj   +1 more source

Hypothesis exploration with visualization of variance. [PDF]

, 2014
BackgroundThe Consortium for Neuropsychiatric Phenomics (CNP) at UCLA was an investigation into the biological bases of traits such as memory and response inhibition phenotypes-to explore whether they are linked to syndromes including ADHD, Bipolar ...
Bilder, Robert M, Congdon, Eliza, Parker, Douglass Stott   +2 more
core   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Screening Experiments and Static Scale Inhibition Performance Evaluation of Scale Inhibitors for Synchronous Condenser Circulating Cooling Water

发电技术
ObjectivesDuring the operation of the circulating cooling water of the regulating camera, the concentration effect leads to the scaling of the heat exchanger and the cooling water packing, which affects the safe and stable operation of the regulating ...
LI Guobin, ZHANG Liang, XIE Qiang, HU Zishu, XIA Zhonglin, ZHAO Ju, ZHANG Yuling, MA Shuangchen   +7 more
doaj   +1 more source

Collective and single cell behavior in epithelial contact inhibition [PDF]

, 2011
Control of cell proliferation is a fundamental aspect of tissue physiology central to morphogenesis, wound healing and cancer. Although many of the molecular genetic factors are now known, the system level regulation of growth is still poorly understood.
A. Puliafito, A. Sigal, Abercrombie, Abercrombie, B. I. Shraiman, Castor, Chaffer, Chen, D. K. Fygenson, Farhadifar, Fournier, Gaush, Guarino, Halbleib, Heckman, Huang, Jamora, Janmey, L. Hufnagel, Lecuit, Leevers, Mark, Martz, Matsubayashi, Minami, Nelson, Orsulic, P. Neveu, Pan, Petitjean, Pugacheva, Rauzi, Rothen-Rutishauser, S. Streichan, Sakisaka, Schwartz, Takai, Tokumaru, Yamada, Yeung, Yu, Zeng, Zhao   +42 more
core   +4 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Co-targeting HGF/cMET Signaling with MEK Inhibitors in Metastatic Uveal Melanoma. [PDF]

, 2017
Patients with metastatic uveal melanoma usually die within 1 year of diagnosis, emphasizing an urgent need to develop new treatment strategies. The liver is the most common site of metastasis.
Aplin, Andrew E., Cheng, Hanyin, Chua, Vivian, Davies, Michael A., Kageyama, Ken, Liao, Connie, Purwin, Timothy J., Sato, Takami, Terai, Mizue   +8 more
core   +2 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Chemical weed control in triticale (x Triticosecale Wittmack): review of five years of field experiments [PDF]

, 2013
During 5 subsequent growing seasons field experiments were carried out at the experimental farm of the University College Ghent (Belgium) to evaluate the selectivity and efficacy of herbicides applied for chemical weed control in triticale (x ...
Derycke, Veerle, Haesaert, Geert, Latré, Joos   +2 more
core