Results 201 to 210 of about 11,235,090 (347)

Chicken intramuscular preadipocyte-derived exosome miR125b-5p promotes lipogenic differentiation of skeletal muscle satellite cells. [PDF]

Poult Sci
Du J, Kong L, Cui J, Jiang W, Ma T, Yang Q, Huang X, Liu D, Wang W, Sun Y.   +9 more
europepmc   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Correction: magnesium isoglycyrrhizinate ameliorates high fructose-induced liver fibrosis in rat by increasing miR-375-3p to suppress JAK2/STAT3 pathway and TGF-β1/Smad signaling. [PDF]

Acta Pharmacol Sin
Yang YZ, Zhao XJ, Xu HJ, Wang SC, Pan Y, Wang SJ, Xu Q, Jiao RQ, Gu HM, Kong LD.   +9 more
europepmc   +1 more source

Scale Deposit Inhibitor for Kraft Digester.

JAPAN TAPPI JOURNAL, 1998
Hitoshi Ito, Masaru Okamoto
openaire   +2 more sources

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Co-delivery of endometrial mesenchymal stem cells and macrophages with an electrospun patch suppresses endometrial fibrosis via IL-10 related signaling. [PDF]

Front Immunol
An J, Li S, Ma T, Chen Y, Santerre JP, Wang W, Ma P, Zhang X.   +7 more
europepmc   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Evaluation of Drug-Drug Interaction Potential Between the Oral Antibiotic Zoliflodacin and the CYP3A4 Inhibitor Itraconazole: A Phase 1 Study in Healthy Participants. [PDF]

Clin Transl Sci
Luckey A, Larson KB, Rayad N, Heep M, Delhomme S, Kornmann G, Mueller JP, O'Donnell JP, O'Brien S, Fuhr R, Gillon JY.   +10 more
europepmc   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

γ-Glutamylcyclotransferase Depletion Induces p15^INK4b and p21^Cip1-mediated Senescence <i>via</i> TGF-β2/SMAD3 Pathway Activation in Breast Cancer Cells. [PDF]

Cancer Genomics Proteomics
Kubota S, Ii H, Isono T, Kusaba T, Nagasawa M, Wada A, Kobayashi K, Yamanaka K, Mori M, Taniguchi K, Nakata S, Kageyama S.   +11 more
europepmc   +1 more source