Results 81 to 90 of about 1,079,684 (305)

hMENA11a contributes to HER3-mediated resistance to PI3K inhibitors in HER2-overexpressing breast cancer cells. [PDF]

, 2015
Human Mena (hMENA), an actin regulatory protein of the ENA/VASP family, cooperates with ErbB receptor family signaling in breast cancer. It is overexpressed in high-risk preneoplastic lesions and in primary breast tumors where it correlates with HER2 ...
Circo, R, De Maria, R, Di Benedetto, A, Di Modugno, F, Matteoni, S, Melchionna, R, Mottolese, M, Nisticò, P. 1., Palermo, Belinda, Soddu, S, Spada, Sheila, Trono, P   +11 more
core   +2 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Release of cholesterol-rich particles from the macrophage plasma membrane during movement of filopodia and lamellipodia. [PDF]

, 2019
Cultured mouse peritoneal macrophages release large numbers of ~30-nm cholesterol-rich particles. Here, we show that those particles represent fragments of the plasma membrane that are pulled away and left behind during the projection and retraction of ...
Fong, Loren G, He, Cuiwen, Heizer, Patrick J, Hu, Xuchen, Jiang, Haibo, Jung, Rachel S, Tontonoz, Peter, Tu, Yiping, Weston, Thomas A, Wohlschlegel, James A, Young, Brian D, Young, Stephen G   +11 more
core   +3 more sources

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Synthesis and Performance Evaluation of Modified Polyaspartic-Acid-Based Scale Inhibitor

Energies
This paper focuses on the selection and application of scale inhibitor by studying the problem of pipeline scaling in geothermal well development. Adding scale inhibitor can effectively reduce the treatment cost and achieve a good scale resistance effect,
WenLong Gao, LiWei Sun, Miao Li, XiAn Ye, QingChun Gao, DongLiang Kong, JunPu An, KuoBo Wang, Fan Yang   +8 more
doaj   +1 more source

Prediction and Inhibition of Inorganic Salt Formation under Static and Dynamic Conditions – Effect of Pressure, Temperature, and Mixing Ratio

International Journal of Technology, 2016
As a result of waterflooding, inorganic salt precipitation occurs in the different parts of an oil production system, thereby leading to damage of production equipment. Different parameters affect the kinetics of salt precipitation.
Azizollah Khormali, Dmitry G. Petrakov, Anar R. Farmanzade   +2 more
doaj   +1 more source

Experimental Study on Boiler Scales Cleaning Using Hydrochloric and Citric Acids [PDF]

Engineering and Technology Journal, 2012
The effect of hydrochloric acid and citric acid was studied experimentally for boiler chemical cleaning to determine the dissolved scale by using carbon steel samples of water-side boiler tubes sections ,different concentrations of hydrochloric acid HCL ...
Dina Raheem, Janet Lazer
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Evaluation Efficiency of Barium Sulfate Scale Inhibitors by Electrochemical Impedance Spectroscopy

International Journal of Electrochemical Science, 2016
The electrochemical behaviour of carbon API 5L X70 grade steel electrode towards barium sulfate scaling and scaling inhibitors is investigated in this paper.
Karima Labraoui-Djallal, Moussa Bounoughaz   +1 more
doaj   +1 more source