Results 141 to 150 of about 807,423 (305)

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

Exact tail asymptotics in bivariate scale mixture models [PDF]

open access: yes, 2018
Let (X, Y) = (RU 1, RU 2) be a given bivariate scale mixture random vector, with R > 0 independent of the bivariate random vector (U 1, U 2). In this paper we derive exact asymptotic expansions of the joint survivor probability of (X, Y) assuming that R ...
Hashorva, Enkelejd
core  

Scaling Laws for Fine-Grained Mixture of Experts

open access: yesCoRR
Mixture of Experts (MoE) models have emerged as a primary solution for reducing the computational cost of Large Language Models. In this work, we analyze their scaling properties, incorporating an expanded range of variables. Specifically, we introduce a new hyperparameter, granularity, whose adjustment enables precise control over the size of the ...
Jakub Krajewski   +11 more
openaire   +3 more sources

Viscoelastic Characteristics and Mechanical Performances of Asphalt Mastic and Mixtures with Fly Ash from Municipal Solid Waste Incineration Residues

open access: yesBuildings
The extraction and utilization of non-renewable mineral resources impose significant transportation and economic challenges in infrastructure construction.
Ling Xu   +4 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Modeling Farmers' Use of Market Advisory Services

open access: yes
In an effort to improve marketing of their products, many farmers use market advisory services (MAS). To date, there is only fragmented anecdotal information about how farmers actually use the recommendations of market advisory services in their ...
Pennings, Joost M.E.   +2 more
core  

In-cylinder flow and combustion studies in an air-assisted direct injection gasoline engine

open access: yes, 2004
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.In-cylinder flows and CAI combustion were investigated in a single cylinder, air-assisted gasoline direct injection engine.
Leach, Ben Thomas
core  

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Practical classification methods for indoor positioning [PDF]

open access: yes, 2012
Location awareness is of primary importance in a wealth of applications such as transportation, mobile health systems, augmented reality and navigation.
Mihaylova, Lyudmila   +2 more
core  

Home - About - Disclaimer - Privacy