Results 31 to 40 of about 18,044 (270)

A Bayesian generalized log-normal model to dynamically evaluate the distribution of pesticide residues in soil associated with population health risks

Environment International, 2018
Exploring better models for evaluating the distribution of pesticide residues in soil and sediment is necessary to assess and avoid population health risk.
Zijian Li
doaj   +1 more source

Sequences of elliptical distributions and mixtures of normal distributions

, 2006
Two conditions are shown under which elliptical distributions are scale mixtures of normal distributions with respect to probability distributions. The issue of finding the mixing distribution function is also considered.
Marín Díazaraque, Juan Miguel, Gómez Villegas, Miguel Ángel, Gómez Sánchez-Manzano, Eusebio, Gómez-Sánchez-Manzano, E., Gómez-Villegas, M.A., Marín, J.M.   +5 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Bayes Estimation for the Mean Matrix of the SSMESN Family of Matrix Variate Distributions

Austrian Journal of Statistics
In this paper, the problem of finding a Bayes estimation for the mean matrix of the scale and shape mixtures of matrix variate extended skew normal distributions is considered, and its applications in the multivariate linear regression and the stress ...
Amir Rezaei, Fatemeh Yousefzadeh
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

A Class of Scale Mixtured Normal Distribution

Journal of Biometrics & Biostatistics, 2016
A class of scale mixtured normal distribution with lifetime probability distributions has been proposed in this article. Different moments, characteristic function and shape characteristics of these proposed probability distributions have also been provided. The scale mixture of normal distribution is extensively used in Biostatistical field.
openaire   +1 more source

Inference in two-piece location-scale models with Jeffreys priors [PDF]

, 2011
This paper addresses the use of Jeffreys priors in the context of univariate threeparameter location-scale models, where skewness is introduced by differing scale parameters either side of the location.
Rubio, Francisco J., Steel, Mark F. J.
core