Results 111 to 120 of about 5,388,952 (345)
RATIO-SCALE ELICITATION OF DEGREES OF BELIEF [PDF]
Most research on rule-based inference under uncertainty has focused on the normative validity and efficiency of various belief-update algorithms. In this paper we shift the attention to the inputs of these algorithms, namely, to the degrees of beliefs ...
Schocken, Shimon
core
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
On the Scaling Ratios for Siegel Disks [PDF]
The boundary of the Siegel disk of a quadratic polynomial with an irrationally indifferent fixed point and the rotation number whose continued fraction expansion is preperiodic has been observed to be self-similar with a certain scaling ratio. The restriction of the dynamics of the quadratic polynomial to the boundary of the Siegel disk is known to be ...
openaire +3 more sources
Automatic comparison of global children’s and adult songs supports a sensorimotor hypothesis for the origin of musical scales [PDF]
Music throughout the world varies greatly, yet some musical features like scale structure display striking crosscultural similarities. Are there musical laws or biological constraints that underlie this diversity?
Fujii, Shina +4 more
core +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
This paper addresses the challenge of accurately classifying sleepiness levels based on the Karolinska Sleepiness Scale (KSS) using Eye Aspect Ratio (EAR) data, especially when class imbalance leads to biased predictions.
Ahmad Zaini +3 more
doaj +1 more source
Next‐generation proteomics improves lung cancer risk prediction
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Periodic Solutions for Gause-Type Ratio-Dependent Predator-Prey Systems with Delays on Time Scales [PDF]
Xiaoquan Ding, Hongyuan Liu, Fengye Wang
openalex +1 more source

