Results 111 to 120 of about 5,116,539 (328)
The String Landscape, Black Holes and Gravity as the Weakest Force
, 2006 We conjecture a general upper bound on the strength of gravity relative to gauge forces in quantum gravity. This implies, in particular, that in a four-dimensional theory with gravity and a U(1) gauge field with gauge coupling g, there is a new ...
A. Adams +10 more
core +1 more source
Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
Molecular Oncology, EarlyView.The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova +18 more
wiley +1 more source
WIND-TUNNEL INVESTIGATION TO DETERMINE THE CRITICAL ADVANCE RATIO OF THE 8/31-SCALE MCDONNELL MODEL 82 CONVERTIPLANE ROTOR [PDF]
, 1953 HANS K. DOETSCH, LEON MARK
openalex +1 more source
Molecular Oncology, EarlyView.This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu +12 more
wiley +1 more source
The power of Bayesian evidence in astronomy
, 2011 We discuss the use of the Bayesian evidence ratio, or Bayes factor, for model selection in astronomy. We treat the evidence ratio as a statistic and investigate its distribution over an ensemble of experiments, considering both simple analytical examples
Berger +24 more
core +1 more source
Molecular Oncology, EarlyView.This nationwide study evaluated KRAS and NRAS mutations in 10 754 Turkish patients with metastatic colorectal cancer. The results revealed a mutation frequency of 51.1%, with 46.6% having KRAS mutations, 4.5% having NRAS mutations, and 48.5% being wild‐type for both.
Gozde Kavgaci +6 more
wiley +1 more source
Automatic comparison of global children’s and adult songs supports a sensorimotor hypothesis for the origin of musical scales [PDF]
, 2019 Music throughout the world varies greatly, yet some musical features like scale structure display striking crosscultural similarities. Are there musical laws or biological constraints that underlie this diversity?
Fujii, Shina +4 more
core +1 more source
Scale convergence as a criterion for rescaling: Information integration with difference, ratio, and averaging tasks [PDF]
, 1974 Michael H. Birnbaum, Clairice T. Veit
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Molecular Oncology, EarlyView.This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh +8 more
wiley +1 more source
TRPM8 levels determine tumor vulnerability to channel agonists
Molecular Oncology, EarlyView.TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo +18 more
wiley +1 more source