Results 91 to 100 of about 984,019 (267)

Safe operating space for humanity at a regional scale

open access: yesEcology and Society, 2018
The planetary boundaries framework defined safe limits to human impacts on essential Earth-system processes. Subsequent assessments concluded that impacts exceed most delineated boundaries.
John F. McLaughlin
doaj   +1 more source

Scale space detector for analyzing spatiotemporal ventricular contractility and nuclear morphogenesis in zebrafish. [PDF]

open access: yesiScience, 2022
Teranikar T   +9 more
europepmc   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

open access: yesFEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata   +6 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Fine-Scale Space-Time Cluster Detection of COVID-19 in Mainland China Using Retrospective Analysis. [PDF]

open access: yesInt J Environ Res Public Health, 2021
Xu M   +7 more
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Color Area Morphology Scale-Spaces [PDF]

open access: yes, 2010
The use of morphological scale-spaces has become a popular tool for the multiscale analysis of grey-scale images. However, in common with other morphological techniques, their extension to color and other multichannel images is not straightforward because of the absence of an unambiguous ordering.
openaire   +2 more sources

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