Results 91 to 100 of about 15,521,488 (377)

A cubed-sphere based method for global and regional modeling of the lithospheric magnetic field

open access: yesEarth and Planetary Physics
The Earth’s magnetic field, which has been extensively observed from ground to satellite altitudes over several decades, originates from multiple sources, such as the core dynamo, the conductive mantle, the magnetized lithosphere, and the space current ...
Liang Yin   +5 more
doaj   +1 more source

A network for multiscale image segmentation [PDF]

open access: yes, 1988
Detecting edges of objects in their images is a basic problem in computational vision. The scale-space technique introduced by Witkin [11] provides means of using local and global reasoning in locating edges.
Malik, Jitendra, Perona, Pietro
core  

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

An alternative regularization approach for modeling the regional lithospheric magnetic field from satellite magnetic measurements by the spherical equivalent source method and its application in Africa

open access: yesEarth and Planetary Physics
The equivalent source (ES) method in the spherical coordinate system has been widely applied to processing, reduction, field modeling, and geophysical and geological interpretation of satellite magnetic anomaly data.
JiangSong Gui   +7 more
doaj   +1 more source

La question des échelles en géohistoire. Les bureaux de la poste aux lettres du XVIIIe siècle à nos jours

open access: yesCybergeo, 2018
Starting from a practice of research that has been going back for years on the question of the use of scales in geohistorical works, this text offers a reflection on the plays of scale, as well as on the question of the MAUP (modifiable areal unit ...
Nicolas Verdier, Ludovic Chalonge
doaj   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Revised global vertically integrated remanent magnetization model of the oceanic lithosphere with comparison to LCS-1 model and MSS-1 magnetic measurements

open access: yesEarth and Planetary Physics
The lithospheric magnetic field is an important component of the geomagnetic field, and the oceanic lithosphere exhibits distinct characteristics. Because of its formation mechanisms, evolutionary history, and geomagnetic field polarity reversals, the ...
ShiDa Sun   +5 more
doaj   +1 more source

Coseismic Rupture Geometry and Slip Rupture Process During the 2018 Mw 7.1 Anchorage, South‐Central Alaska Earthquake: Intraplate Normal Faulting by Slab Tear Constrained by Geodetic and Teleseismic Data

open access: yesEarth and Space Science, 2020
The Mw 7.1 Anchorage earthquake on 30 November 2018 beneath the south‐central Alaska is a rare intermediate‐depth event larger than Mw 7 that occurred in a complex subduction region, where the young Yakutat oceanic terrane wedges in the continental ...
Ping He   +4 more
doaj   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

A phase-space study of jet formation in planetary-scale fluids

open access: yes, 2009
The interaction between planetary waves and an arbitrary zonal flow is studied from a phase-space viewpoint. Using the Wigner distribution, a planetary wave Vlasov equation is derived that includes the contribution of the mean flow to the zonal potential
Wordsworth, Robin D.
core   +2 more sources

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