Results 71 to 80 of about 984,019 (267)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A 100-degree lithospheric magnetic field model constructed using MSS-1, Swarm-A, and CHAMP satellite data

Earth and Planetary Physics
By combining data from the Challenging Minisatellite Payload (CHAMP), Swarm-A, and newest Macau Science Satellite-1 (MSS-1) missions, we constructed a lithospheric magnetic field model up to spherical harmonic degree N = 100.
JiaXuan Zhang, Yan Feng, Pan Zhang, YuXuan Lin, XinWu Li, Ya Huang   +5 more
doaj   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Scale Spaces on Lie Groups [PDF]

, 2007
In the standard scale space approach one obtains a scale space representation u:R of an image by means of an evolution equation on the additive group (R d ,¿+¿). However, it is common to apply a wavelet transform (constructed via a representation of a Lie-group G and admissible wavelet ¿) to an image which provides a detailed overview of the group ...
Duits, R., Burgeth, B.
openaire   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Revealing Blind Faults Through High‐Resolution Imaging of Shallow Structures: A Case Study on Chenghai Fault, Yunnan, China

Geophysical Research Letters
Blind faults pose significant seismic hazards because they remain hidden beneath the surface and are often unrecognized until they generate large earthquakes. High‐resolution shallow velocity models are essential for imaging these blind structures.
Lei Qin, Hongrui Qiu, Hongfeng Yang, Fenglin Niu, Nori Nakata, Xiong Xiong   +5 more
doaj   +1 more source

Manufacturing process of water-soluble salt-based ceramic cores based on vat photopolymerization

Journal of Advanced Ceramics
Water-soluble salt-based ceramic cores can be recycled and have excellent high-temperature chemical stability. In this work, vat photopolymerization was successfully applied to water-soluble salt-based ceramic cores for the first time.
Yuzhen Zhang, Wenyan Duan, Yue Gu, Xingyao Sun, Shan Li, Bingshan Liu, Gong Wang   +6 more
doaj   +1 more source

Scale Space Calibrates Present and Subsequent Spatial Learning in Barnes Maze in Mice. [PDF]

eNeuro, 2023
Tachiki Y, Suzuki Y, Kurahashi M, Oki K, Mavuk Ö, Nakagawa T, Ishihara S, Gyoten Y, Yamamoto A, Imayoshi I.   +9 more
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source