Results 181 to 190 of about 3,018,546 (285)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

A width centric image to mechanics framework for assessing advance grouting with T_MSE adaptive width segmentation and lab scale validation. [PDF]

Sci Rep
Zhu P, Zhang Z, Chen T, Wang R, Zhang D, Zhu L, Guo J.   +6 more
europepmc   +1 more source

A Large-Scale Validation of an Improved Embryo-Rescue Protocol for the Obtainment of New Table-Grape Seedless Genotypes. [PDF]

Plants (Basel), 2023
Chiaromonte E, Bottalico G, Lanotte P, Campanale A, Montilon V, Morano M, Saponari A, Pirolo CS, Gerin D, Faretra F, Pollastro S, Savino VN.   +11 more
europepmc   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Compassion Scale: factor structure and scale validation in Hong Kong adolescents. [PDF]

Front Psychol
Ngai SS, Cheung CK, Ng YH, Guo HY, Du HL, Chen C, Wong LM, Zhou QS, Pang WT.   +8 more
europepmc   +1 more source

Eco-Friendly Pavements Manufactured from Mixed Recycled Aggregates Obtained from Construction and Demolition Waste: An Industrial-Scale Validation. [PDF]

Materials (Basel), 2023
Contreras-Llanes M, Gázquez MJ, Romero M.   +2 more
europepmc   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Ikelos-Rating Scale: Validation of a Behavioural Severity Marker in REM Sleep Behaviour Disorder. [PDF]

J Sleep Res
Stotz S, Bes F, Kunz D.
europepmc   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

The EVENDOL Pain Scale Validation for Acute Non-Procedural Neonatal Pain in Term Neonates: Reliability and Validity in Maternity Wards. [PDF]

Paediatr Neonatal Pain
Calamy L, Fournier-Charrière E, Martret P, Cimerman P, Boithias C, Debillon T, Carbajal R, Falissard B, Walter-Nicolet E.   +8 more
europepmc   +1 more source