Results 101 to 110 of about 9,149,613 (368)

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Improving the scaling normalization for high-density oligonucleotide GeneChip expression microarrays

open access: yesBMC Bioinformatics, 2004
Background Normalization is an important step for microarray data analysis to minimize biological and technical variations. Choosing a suitable approach can be critical.
Lu Chao
doaj   +1 more source

Scaling in Plasticity-Induced Cell-Boundary Microstructure: Fragmentation and Rotational Diffusion

open access: yes, 2003
We develop a simple computational model for cell boundary evolution in plastic deformation. We study the cell boundary size distribution and cell boundary misorientation distribution that experimentally have been found to have scaling forms that are ...
A. Godfrey   +17 more
core   +1 more source

Superscaling of Inclusive Electron Scattering from Nuclei [PDF]

open access: yes, 1999
We investigate the degree to which the concept of superscaling, initially developed within the framework of the relativistic Fermi gas model, applies to inclusive electron scattering from nuclei.
A. Hotta   +52 more
core   +2 more sources

Forecasting at Scale

open access: yesThe American Statistician, 2017
Forecasting is a common data science task that helps organizations with capacity planning, goal setting, and anomaly detection. Despite its importance, there are serious challenges associated with producing reliable and high quality forecasts — especially when there are a variety of time series and analysts with expertise in time series modeling are ...
Benjamin Letham, Sean J. Taylor
openaire   +1 more source

Scaling Cosmology [PDF]

open access: yesGeneral Relativity and Gravitation, 2003
We show that with the help of a suitable coupling between dark energy and cold dark matter it is possible to reproduce any scaling solution $ _{X}\propto _{M}a^ $, where $ _{X}$ and $ _{M}$ are the densities of dark energy and dark matter, respectively. We demonstrate how the case $ = 1$ alleviates the coincidence problem. Future observations of
Winfried Zimdahl, Diego Pavón
openaire   +4 more sources

Evolutionary interplay between viruses and R‐loops

open access: yesFEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi   +4 more
wiley   +1 more source

Corrosion and Scaling Potential in drinking water distribution system: a case study of Mashhad, 2017 [PDF]

open access: yesPizhūhish dar Bihdāsht-i Muḥīṭ., 2019
Background and objectives: Corrosion and Scaling in distribution network pipes is one of the most important indices in water quality evaluation and one of the most common environmental phenomena that deteriorate water quality, color, odor, taste and also
Hosein Alidadi   +7 more
doaj   +1 more source

The scale of predictability [PDF]

open access: yesJournal of Econometrics, 2012
We view economic time series as the result of a cascade of shocks occurring at dierent times and dierent frequencies. In agreement with this premise, we suggest that equilibrium (predictive) relations that are found to be elusive when using raw data may hold true for dierent layers, components, or details, in the cascade of shocks aecting economic time
Federico M. Bandi   +4 more
openaire   +4 more sources

Purification tags markedly affect self‐aggregation of CPEB3

open access: yesFEBS Letters, EarlyView.
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito   +6 more
wiley   +1 more source

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