Results 81 to 90 of about 3,449,394 (355)

Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms

FEBS Letters, EarlyView.
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze, Stéphane Canaan, Alexandre Gouzy, Pierre Santucci   +3 more
wiley   +1 more source

Hierarchical Scaling in Systems of Natural Cities

Entropy, 2018
Hierarchies can be modeled by a set of exponential functions, from which we can derive a set of power laws indicative of scaling. The solution to a scaling relation equation is always a power law.
Yanguang Chen, Bin Jiang
doaj   +1 more source

Fast and Accurate Model Scaling [PDF]

arXiv, 2021
In this work we analyze strategies for convolutional neural network scaling; that is, the process of scaling a base convolutional network to endow it with greater computational complexity and consequently representational power. Example scaling strategies may include increasing model width, depth, resolution, etc. While various scaling strategies exist,
arxiv  

Universal finite-size scaling amplitudes in anisotropic scaling

, 2001
Phenomenological scaling arguments suggest the existence of universal amplitudes in the finite-size scaling of certain correlation lengths in strongly anisotropic or dynamical phase transitions.
Alcaraz F C, Alcaraz F C, Bausch R, Binder K, Bulirsch R, Cardy J L, Cardy J L, Cardy J L, Carlon E, de Dominicis C, Doi M, Doi M, Droz M, Fisher M E, Fridkin V, Grassberger P, Grassberger P, Grassberger P, Henkel M, Henkel M, Henkel M, Henkel M, Henkel M, Hertz J A, Hinrichsen H, Hooyberghs J, Howard M J, Izmailian N Sh, Janssen H K, Kamphorst Leal da Silva J, Krebs K, Krebs K, Lee B P, Malte Henkel, Marro J, Mendes J F F, Mendes J F F, Neubert B, Peliti L, Peliti L, Peschel I, Privman V, Sachdev S, Schmittmann B, Schütz G M, Selke W, Simon H, Ulrich Schollwöck, Weigel M, Yeomans J M, Ódor G   +50 more
core   +1 more source

Super-roughening versus intrinsic anomalous scaling of surfaces [PDF]

, 1997
In this paper we study kinetically rough surfaces which display anomalous scaling in their local properties such as roughness, or height-height correlation function.
F. Family, H. Leschhorn, J. Amar, J. Krug, J. Krug, J. M. López, J. M. López, J. Schmittbuhl, Juan M. López, K. Falconer, M. Plischke, M. Schroeder, Miguel A. Rodríguez, P. Meakin, Rodolfo Cuerno, S. Das Sarma, S. Das Sarma, S. F. Edwards, S. Roux, T. Halpin-Healey   +19 more
core   +2 more sources

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

FEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma, Jennifer R. Deuis, Xinying Jia, Theo Crawford, Sassan Rahnama, Eivind A. B. Undheim, Irina Vetter, Yanni K. ‐Y. Chin, Mehdi Mobli   +8 more
wiley   +1 more source

Scale [PDF]

Victorian Literature and Culture, 2018
Entry for the special Keywords issue of Victorian Literature and Culture.
openaire   +1 more source

Scaling of Metabolic Scaling within Physical Limits

Systems, 2014
Both the slope and elevation of scaling relationships between log metabolic rate and log body size vary taxonomically and in relation to physiological or developmental state, ecological lifestyle and environmental conditions.
Douglas S. Glazier
doaj   +1 more source

Identification of novel small molecule inhibitors of ETS transcription factors

FEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla, Zary Forghany, Jin Ma, Johan G. Hollander, Ruta Nachane, Karoly Szuhai, Pancras C. W. Hogendoorn, Peter ten Dijke, Dipen Shah, David A. Baker   +9 more
wiley   +1 more source

Beyond Positive Scaling: How Negation Impacts Scaling Trends of Language Models [PDF]

arXiv, 2023
Language models have been shown to exhibit positive scaling, where performance improves as models are scaled up in terms of size, compute, or data. In this work, we introduce NeQA, a dataset consisting of questions with negation in which language models do not exhibit straightforward positive scaling. We show that this task can exhibit inverse scaling,
arxiv