Results 131 to 140 of about 1,697,083 (297)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Entanglement and dynamical scaling laws in quantum superabsorption

open access: yesPhysical Review Research
Quantum batteries (QBs) exploit collective quantum resources to surpass the limits of classical energy storage and power delivery. We analyze N-qubit cavity-coupled QBs governed by Dicke and Tavis-Cummings models under Gaussian driving and open-system ...
Juan David Álvarez-Cuartas   +1 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

A SCALING LIMIT FOR t-SCHUR MEASURES

open access: yesKyushu Journal of Mathematics, 2005
We introduce a generalization of the Schur measure. And we give a combinatorial interpretation to this generalized measure and prove that a scaling limit for this measure is given by the Tracy-Widom distribution.
openaire   +4 more sources

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Scaling limits in interacting particle systems

open access: yes
SCALING LIMITS IN INTERACTING PARTICLE SYSTEMS Scaling limits in interacting particle systems / Kern, Julian (Rights reserved) (-
Kern, Julian
core  

Exact Finite-Size Scaling and Corrections

open access: yes, 2007
The Ising model in two dimensions with the special boundary conditions of Brascamp and Kunz is analysed. Leading and sub-dominant scaling behaviour of the Fisher zeroes are determined exactly.
W. Janke, R. Kenna, To Scaling In
core  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Windternet : Designing grid-liberated servers for regenerative energy communities

open access: yes
Imaginations of server practices that depend on renewable energy, such as wind or solar, highlight alternative paradigms to the fossil fuel intensive, resource hungry computation of cloud regimes.
Zapico, Jorge Luis   +4 more
core   +2 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

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