Results 111 to 120 of about 339,768 (366)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Quasi-Static Voltage Scaling for Energy Minimization with Time Constraints

open access: yes, 2005
Supply voltage scaling and adaptive body-biasing are important tech-niques that help to reduce the energy dissipation of embedded systems. This is achieved by dynamically adjusting the voltage and performance settings according to the application needs ...
Eles, Petru   +9 more
core  

Test equating, scaling, and linking: methods and practices

open access: yes, 2014
This book provides an introduction to test equating, scaling, and linking, including those concepts and practical issues that are critical for developers and all other testing professionals.
Kolen, Michael J, Brennan, Robert L
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Long-term memories of developed and emerging markets: Using the scaling analysis to characterize their stage of development [PDF]

open access: yes
The scaling properties encompass in a simple analysis many of the volatility characteristics of financial markets. That is why we use them to probe the different degree of markets development.
T. Di Matteo   +2 more
core  

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Scaling Of Discrete Element Model Parameters In Uniaxial Test Simulation

open access: yes, 2013
This study investigates the scaling of DEM model parameters that are necessary to produce scale independent predictions for cohesionless and cohesive solid under confined compression and unconfined compression to failure.
Sun, Jin   +3 more
core  

Scaling test of two-flavor O(a)-improved lattice QCD

open access: yes, 2008
We report on a scaling test of several mesonic observables in the non-perturbatively O(a) improved Wilson theory with two flavors of dynamical quarks.
Sommer, Rainer   +8 more
core   +1 more source

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