Results 141 to 150 of about 186,440 (256)

Synaptic Dysfunction in the Anterior Cingulate Cortex Underlies Pain‐Anxiety Comorbidity in a Mandibular Asymmetry Mouse Model

Advanced Science, EarlyView.
This study establishes a mandibular asymmetry (MA) mouse model that recapitulates chronic orofacial pain and anxiety comorbidity. Anterior cingulate cortex (ACC) hyperactivation and synaptic dysfunction are identified as central neural mechanisms underlying these pathologies, with chemogenetic inhibition of ACC CaMKII+ neurons effectively reversing ...
Zhaoyichun Zhang, Yanran Zhang, Jialin Si, Honghui Mao, Feng He, Jin Ning, Guaiguai Ma, Xiaohua Chen, Haoxiang Xiao, Yuanyuan Zhu, Haifeng Zhang, Yifan Lu, Qian Liu, Meng Nian, Shiquan Sun, Shibin Yu, Shengxi Wu, Ze Fan, Zuolin Jin, Jing Huang   +19 more
wiley   +1 more source

Photodynamic Therapy in Treatment of Patients with Severe Erosive Pustular Dermatosis of Scalp

Journal of Dermatology and Dermatologic Surgery
Erosive pustular dermatosis (EPD) is a rare inflammatory condition characterized by sterile pustules, crusting, and cicatricial alopecia. A 99-year-old Caucasian male with extensive sun damage and a history of multiple skin cancers presented with ...
Taraneh Fazel, Destinee C. Elliott, Francesca L. Veon, Lindsey Collins   +3 more
doaj   +1 more source

A Minimally Invasive Framework Reveals Region‐Specific Cerebrovascular Remodeling in Aging Using Intravital Functional Ultrasound Imaging and Ultrasound Localization Microscopy (fUS‐ULM)

Advanced Science, EarlyView.
A high‐resolution intravital imaging platform combining functional ultrasound and localization microscopy enables longitudinal, minimally invasive assessment of cerebrovascular function in aging studies. The present investigation reveals aging‐related reductions in neurovascular coupling, arteriole‐to‐venule ratio and vascular density, introducing a ...
Sharon Negri, Adam Nyul‐Toth, Madison Milan, Eva Troyano‐Rodriguez, Sherwin Tavakol, Jennifer Ihuoma, Zeke Reyff, Rakesh Rudraboina, Rafal Gulej, Raymond Jang, Anna Csiszar, Zoltan Ungvari, Audrey Cleuren, David R Miller, Andriy Yabluchanskiy, Mickael Tanter, Stefano Tarantini   +16 more
wiley   +1 more source

Mechanical Stretch‐Induced Interlayer Coordination between MMP2 and COL17A1 Exacerbates Regenerative Exhaustion in Skin

Advanced Science, EarlyView.
Regeneration reaches a hidden limit under mechanical stretch. Prolonged tension alters dermal–epidermal communication, exhausting epidermal stem cells via MMP2–COL17A1 signaling. MMP2 inhibition by Marimastat preserves adhesion and regenerative capacity, offering a potential strategy to overcome the inherent boundaries of skin expansion.
Yidan Sun, Qili Qian, Luwen Xu, Bowen Gao, Ting Li, Yin Li, Jiayi Zheng, Qiaoyu Fu, Xi Cheng, Nuo Chen, Sijia Wang, Liang Zhang, Caiyue Liu, Qingfeng Li   +13 more
wiley   +1 more source

An Active, Multimodal Neural Interface for Real‐Time Monitoring of Cortical Electrical, Thermal, and Optical Dynamics

Advanced Science, EarlyView.
A chronically implantable neural interface enables real‐time multimodal monitoring of electrical, thermal, and photodynamic activities. Incorporating silicon‐based transistor arrays with a functional multiplexing strategy and resistive sensors, the device delivers high‐fidelity recordings with long‐term stability and biocompatibility.
Jiahao Li, Yifei Lu, Zhongzheng Li, Lu Jin, Lianjie Zhou, Ke Ding, Junhan Liu, Bofan Hu, Pengchuan Liu, Dongqi An, Fuying Liang, Yuhang Hu, Yuting Shao, Yifan Ding, Lichao Ma, Rui Li, Yongfeng Mei, Rongjun Zhang, Enming Song   +18 more
wiley   +1 more source

Enhanced Protein Synthesis and Hippocampus‐Dependent Memory via Inhibition of YTHDF2‐Mediated m6A mRNA Degradation

Advanced Science, EarlyView.
YTHDF2‐mediated m6A mRNA decay critically regulates learning and memory. Its forebrain‐specific knockout in mice impedes degradation of m6A‐modified mRNAs, enhancing hippocampal synaptic transmission, protein synthesis, and memory. Conversely, hippocampal YTHDF2 reintroduction or SEMA4B reduction reverses this enhancement, while its overexpression ...
Kuan Li, Chen Guo, Xiaoli Wu, Cuiting Wu, Songfen Wu, Si Su, Min Wu, Xidan Zhou, Si Li, Yihui Cui, Tao Zhou   +10 more
wiley   +1 more source

Surgical treatment of massive scalp lesions [PDF]

, 1956
R. R. Braund, John D. Pigott
openalex   +1 more source

Long‐Term Stable Subdural Recordings Enabled by Fibrosis‐Resistant Hydrogel‐Integrated µECoG Arrays

Advanced Science, EarlyView.
An adhesive hydrogel‐integrated micro‐electrocorticography (aGel‐µECoG) array is developed to ensure stable neural recordings by minimizing neuroinflammation and fibrosis during implantation. The hydrogel serves as a biological and mechanical bridge, enabling bioadhesive, reversible, anti‐fibrotic integration with brain tissue.
Lin Chen, Hao Zhong, Linghao Wang, Liju Xu, Wanying Fan, Yongpeng Zhao, Huiling Zhang, Yang Shen, Kai Wu, Xin Fu, Jingxiang Guo, Ke Li, Dong Qiu, Ting Wu   +13 more
wiley   +1 more source

Malignant Peripheral Nerve Sheath Tumor of the Scalp: A Case Report [PDF]

Caspian Journal of Neurological Sciences
Background: Malignant peripheral nerve sheath tumors (MPNSTs) are uncommon tumors typically originating from somatic soft tissues or peripheral nerves. Instances of primary MPNSTs on the scalp are exceedingly rare.
I Wayan Niryana, Putu Eka Mardhika, Steven Awyono, Adi Wismayasa, Ni Made Maharini Rahayu   +4 more
doaj  

Treatment of Scalp Wounds [PDF]

, 1942
E. H. Botterell, Gina D. Jefferson
openalex   +1 more source