Results 41 to 50 of about 13,898 (295)

Crystal dislocations and incorporation of Sc in hydrothermally modified beryl from LCT type pegmatites

open access: yesCommunications Earth & Environment
Pegmatites of the lithium-cesium-tantalum type are widely dismissed as potential scandium hosts. Here we show that beryl from the Bailongshan pegmatite deposit in northwest China contains anomalously high scandium, with scandium oxide reaching up to 1.85 
Tao Hong   +8 more
doaj   +1 more source

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

open access: yesFEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park   +8 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

A basic evaluated neutronic data file for elemental scandium [PDF]

open access: yes, 1992
This report documents an evaluated neutronic data file for elemental scandium, presented in the ENDF/B-VI format. This file should provide basic nuclear data essential for neutronic calculations involving elemental scandium.
Smith, A. B.   +2 more
core   +3 more sources

β-sulfur-engineered biochar mitigates scandium toxicity in wheat: Impacts on growth characteristics, photosynthetic activity, and redox regulation

open access: yesIndustrial Crops and Products
Scandium (Sc) is acknowledged as a toxic substance that negatively impacts crop growth and physiological and biochemical metabolism. The main purpose of the present research was to examine the influence of β-Sulfur-engineered rice husk biochar (βS-MBC ...
Ghulam Murtaza   +8 more
doaj   +1 more source

Concentration and Separation of Scandium from Ni Laterite Ore Processing Streams

open access: yesMetals, 2017
The presence of a considerable amount of scandium in lateritic nickel-cobalt ores necessitates the investigation of possible processing alternatives to recover scandium as a byproduct during nickel and cobalt production.
Şerif Kaya   +3 more
doaj   +1 more source

Use of Ion-Exchange Resins to Adsorb Scandium from Titanium Industry’s Chloride Acidic Solution at Ambient Temperature

open access: yesMetals, 2022
Scandium metal has generated a lot of interest during the past years. This is due to the various crucial applications it has found ground in and the lack of production in countries outside China and Russia. Apart from rare earth ores, scandium is present
Eleni Mikeli   +5 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Assessing the Efficiency of Ion Exchange Resins for the Recovery of Scandium from Sulfuric Acid Leaching Solutions

open access: yesSeparations, 2023
Scandium, a valuable element with restricted production sources mainly situated in China and Russia, is typically obtained as a by-product during the production of various materials.
Aikaterini Toli   +4 more
doaj   +1 more source

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