Results 51 to 60 of about 13,898 (295)

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Prospects for scandium mining in Ukraine

Вісник Київського національного університету імені Тараса Шевченка. Серія Геологія
Background. The prospects for scandium mining in Ukraine are discussed. The important role of scandium in modern industry, as one of the high-tech metals, is highlighted. Methods.
Volodymyr Mykhailov, Olena Andreeva, Vitalii Sydorchuk   +2 more
doaj   +1 more source

Solvent extraction of Sc(III) from sulfuric acid solution by bis(2-ethylhexyl) phosphonic acid in toluene [PDF]

Journal of the Serbian Chemical Society, 2002
Liquid-liquid extraction of scandium(III) from sulfuric acid solution using bis(2-ethylhexyl) phosphinic acid (PIA-8) in toluene has been studied. The extraction of scandium(III) was found to be quantitative with 0.03 M PIA-8 in toluene in the acidic ...
Koladkar Devendra V., Dhadke Purshottam M.   +1 more
doaj   +1 more source

Provenance and tectonic setting of Leuma Field sediments, Coastal Swamp Depobelt, Niger Delta Basin, Nigeria

Journal of Applied Sciences and Environmental Management, 2022
Geochemical analysis of sediments recovered from NS-1 well and NS-2 well, Leuma Field, Coastal Swamp Depobelt, Niger Delta Basin was done to establish tectonic setting and provenance.
N.S. Igbinigie, A. Ogbamikhumi
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Scandium-bearing coals of the Shaim oil and gas region of the West Siberian basin

Известия Томского политехнического университета: Инжиниринг георесурсов
Relevance. The need to identify new sources of industrial production of strategic metals that are critical for modern technologies. Aim. To study the geological and geochemical conditions that led to the formation of anomalous scandium concentrations in
Sergey I. Arbuzov, Sergey S. Ilenok, Andrey S. Toropov, Alexey S. Kholodov   +3 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Radiometric Analysis of Scandium

, 1967
In continuation of the study on the estimation of scandium as pyrophosphate by radiometric procedure a lower limit of \(\sim\) 55\(\gamma\) has been reached using p32 a measuring indicator.
K. N. Dutta, B. C. Purkayastha
core   +1 more source

Method of Producing Scandium Concentrate [PDF]

, 2020
Изобретение относится к технологии попутного извлечения скандия из продуктивных растворов, образующихся при переработке редкометальных руд, содержащих скандий.
Кириллов, Е. В., Рычков, В. Н., Буньков, Г. М., Смирнов, А. Л., Кириллов, С. В., Боталов, М. С.   +5 more
core  

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source