Results 71 to 80 of about 13,898 (295)
Proceedings of the Royal Society of London. Series A, Containing Papers of a Mathematical and Physical Character, 1908 Abstract Scandia is one of the rarest and least known of the recognised rare earths. It was discovered in 1879 by Nilson, who separated it, together with ytterbia, from erbia extracted from euxenite and gadolinite. Later in the same year Cleve extracted scandia from gadolinite, yttrotitanite, and keilhauite, and described the scandium
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Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
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Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
A temperature-resolved assembly of a series of the largest scandium-containing polyoxotungstates
, 2017 The first series of hexameric scandium-substituted polyoxometalates have been isolated from the same reaction by a temperature-resolved crystallization process, which represent the largest scandium-containing polyoxometalates with the largest number of ...
Yan-Jie Qi +4 more
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Advances in Condensed Matter PhysicsThe effect of scandium doping on the structural, electronic, optical, and thermodynamic properties of scandium-doped zirconia (Zr0.875Sc0.125 O1.9375) was investigated by first-principles calculations.
Lemessa Asefa Eressa +1 more
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MetalsThe solvent extraction and separation process for scandium(III) (Sc) and titanium(IV) (Ti) from titanium white waste acid (TWWA) was studied. The influences of process parameters, including extractant type, feed solution acidity, and di(2-ethylhexyl ...
Ran-Ran Zhang, Pin Shao, Ji-Dong Li
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Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
Scandium Master Alloy Production Via Sulfidation and Vacuum Aluminothermic Reduction
, 2023 Scandium is a critical component for high strength aluminum products, yet manufacture is burdened by challenges in metal reduction and alloying. Current best practice begins with generation of an aluminum-scandium master alloy from oxide or halide ...
Stinn, Caspar +5 more
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Molecular Oncology, EarlyView.This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan +8 more
wiley +1 more source
Attitudes of cancer patients toward ctDNA‐based liquid biopsy for follow‐up
Molecular Oncology, EarlyView.This mixed‐methods study explored cancer patients' experiences, knowledge, and preferences regarding ctDNA‐based liquid biopsy for follow‐up. Awareness of ctDNA was low and recall of previous liquid biopsy was imperfect, yet acceptance was high.
Siddharth Chhajlani +7 more
wiley +1 more source