Results 81 to 90 of about 13,195 (290)

Separation of 44Sc from Natural Calcium Carbonate Targets for Synthesis of 44Sc-DOTATATE

Molecules, 2018
The rapid increase in applications of scandium isotopes in nuclear medicine requires new efficient production routes for these radioisotopes. Recently, irradiations of calcium in cyclotrons by α, deuteron, and proton beams have been used. Therefore,
Krzysztof Kilian, Łukasz Cheda, Mateusz Sitarz, Katarzyna Szkliniarz, Jarosław Choiński, Anna Stolarz   +5 more
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source

Green Separation of Scandium and Titanium Using Citric Acid via Organic Complexation Scrubbing

Separations
Aiming at the bottleneck of the difficult scrubbing and separation of scandium and titanium in the solvent extraction process for scandium recovery, a novel strategy for scandium–titanium separation via citrate complex scrubbing is proposed based on the ...
Guangyu Zhang, Weiguang Zhang, Yingxuan Wang, Lexuan Zhang, Xuejiao Cao, Yibing Li, Yang Chen, Yan Wang   +7 more
doaj   +1 more source

Solvent extraction of scandium from lateritic nickel- cobalt ores using different organic reagents

E3S Web of Conferences, 2016
Scandium is the most important and strategic metal that can be recovered as a by-product from lateritic nickel-cobalt ores. In this research, different extractants were investigated in order to extract scandium from a sulfate medium by a using a solvent ...
Ferizoğlu Ece, Kaya Şerif, Topkaya Yavuz A.   +2 more
doaj   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

Method of Producing Scandium Concentrate from Scandium-Containing Solution [PDF]

, 2019
FIELD: metallurgy. SUBSTANCE: invention relates to chemistry and metallurgy, specifically to technology of extracting scandium from productive solutions formed during processing of uranium ore, during their production by method of underground leaching ...
Smyshlyaev, D. V., Poponin, N.j A., Кириллов, Е. В., Буньков, Г. М., Смирнов, А. Л., Боталов, М. С., Kirillov, E. V., Smirnov, A. L., Свирский, И. А., Titova, S. M., Svirskij, I. A., Попонин, Н. А., Rychkov, V. N., Рычков, В. Н., Титова, С. М., Kirillov, S. V., Кириллов, С. В., Botalov, M. S., Смышляев, Д. В., Bunkov, G. M.   +19 more
core   +1 more source

Effect of scandium on cast iron microstructure

, 2019
The objective is to determine if scandium additions can create nodular or compacted graphite iron. Initially, plates of uninoculated cast iron with and without scandium additions were assessed metallographically, and scandium was found to form type D ...
Sanders, Paul G., Langan, Timothy, Coy, Mason, Heidelberger, Erin, Russell, Katherine   +4 more
core   +1 more source