Results 31 to 40 of about 38,704 (246)

Integrating MRI-based tumour staging within the TNM classification system in modern prostate cancer management

Insights into Imaging
MRI has transformed prostate cancer diagnosis, risk stratification, and treatment planning. However, the tumour-node-metastasis (TNM) classification continues to rely exclusively on digital rectal examination (DRE) for clinical T-staging, despite DRE’s ...
Georgios Agrotis, Andrei Purysko, Anwar Padhani, Fredrik Jäderling, Geert Villeirs, Samuel J. Withey, Maarten de Rooij, Tristan Barrett, Ivo G. Schoots   +8 more
doaj   +1 more source

Vascular conspicuity differs among injection protocols and scanner types for canine multiphasic abdominal computed tomographic angiography [PDF]

Veterinary Radiology & Ultrasound, 2018
AbstractMultiphasic multidetector computed tomographic angiography is a standard diagnostic test for canine abdominal vascular disorders. Three imaging protocols have been previously described. The test‐bolus protocol allows precise timing but can be time consuming to perform.
Florence Thierry, Jennifer Chau, Mariano Makara, Swan Specchi, Edoardo Auriemma, Maurizio Longo, Ian Handel, Tobias Schwarz   +7 more
openaire   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Polysplenia Syndrome With Persistent Left Superior Vena Cava: Case Report and Review of the Literature

Global Pediatric Health, 2022
Polysplenia syndrome is an uncommon condition associating several splenic nodules (sometimes polylobed spleen and cases of normal spleen have been described) with a number of malformations that appear between the fourth and sixth week of embryonic ...
El Houss Salma MD, Amsiguine Najwa MD, Tantaoui Mehdi MD, Allali Nazik PhD, Chat Latifa PhD, El Haddad Siham PhD   +5 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Possibilities of transabdominal ultrasonography in the diagnosis of the pediatric gastroesophageal reflux disease

Бюллетень сибирской медицины, 2011
The purpose of the current research is to investigate the diagnostic value of ultrasonography of the pediatric gastroesophageal reflux disease. There were 29 children examined with clinical and endoscopic signs of gastroesophageal reflux in each of three
D. A. Balagansky, A. P. Koshel, M. L. Vrublevskaya   +2 more
doaj   +1 more source

Pancréatite aiguë gestationnelle secondaire à une hypertriglycéridémie majeure : à propos d´un cas

PAMJ Clinical Medicine, 2020
Nous rapportons le cas d'une patiente enceinte de 33 semaines d´aménorrhée qui consulte en urgence pour un syndrome douloureux abdominal aigu avec vomissements, chez qui un examen obstétrical avait objectivé une mort fœtale in utéro.
Ayoub Boubekri, Nourredine Kartit, Walid Atmani, Nawfal Doghmi, Hicham Bakkali   +4 more
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Atteinte hépatique au cours de la maladie de Rendu-Osler: à propos d'un cas et revue de la littérature

The Pan African Medical Journal, 2016
Patiente âgée de 48 ans était hospitalisée pour une cholestase asymptomatique hépatique. Elle rapportait une histoire personnelle et familiale d'récidivante. Le bilan biologique révélait une anémie ferriprive et une cholestase modérée.
Hanen Loukil, Mouna Snoussi, Hela Fourati, Faten Frikha, Raida Ben Salah, Moez Jallouli, Sameh Marzouk, Zeineb Mnif, Zouhir Bahloul   +8 more
doaj   +1 more source