Results 41 to 50 of about 38,704 (246)

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem   +9 more
wiley   +1 more source

Validation of SSDE calculation in a modern CT scanner and correlation with effective dose

open access: yesScientific Reports
This study aims to validate the Size Specific Dose Estimate (SSDE) provided by a modern Computed Tomography (CT) scanner and investigate its correlation with effective dose (E).
Nicola Zancopè   +9 more
doaj   +1 more source

Trichobézoard gastroduodénal: à propos d'un cas

open access: yesThe Pan African Medical Journal, 2018
Le trichobézoard gastroduodénal est une affection rare, dont le diagnostic est facile en présence d'un contexte évocateur. Nous rapportons le cas d'une jeune patiente âgée de 21 ans suivie pour une schizophrénie, admise pour douleur abdominale aiguë ...
Khalid Mazine   +6 more
doaj   +1 more source

The risk of abdominal aortic aneurysm rupture prediction according to computed tomography data

open access: yesВестник медицинского института «Реавиз»: Реабилитация, врач и здоровье, 2023
Background. Abdominal aortic aneurysm – is a widespread disease, which in some cases does not have any specific clinical symptoms, but possible complications of this pathology are characterized by high mortality.
D. Z. Tutova   +4 more
doaj   +1 more source

Distinct Systemic Sclerosis Phenotypes Related to Ethnicity: An Opportunity to Personalize Care?

open access: yesArthritis Care &Research, EarlyView.
Objective The objective is to describe and compare demographic, clinical, and serological characteristics of patients with systemic sclerosis (SSc) according to ethnic background. Methods Participants enrolled in the Canadian Scleroderma Research Group cohort who self‐identified to a single ethnicity group were included.
Danick Goulet   +11 more
wiley   +1 more source

Strain‐Programmable Luminescent Adhesive Patch With Tartrazine‐Mediated Optical Skin Clearing for Photochemical Tissue Bonding

open access: yesAdvanced Functional Materials, EarlyView.
We propose a suture‐complementary approach that integrates optical skin clearing with a strain‐programmable luminescent adhesive patch. Hyaluronic acid promotes transdermal delivery of tartrazine to improve optical clearing and stabilizes its interaction with a photosensitizer. Optical clearing increases the penetration depth of visible light into skin,
Seong‐Jong Kim   +6 more
wiley   +1 more source

Intelligent Orthopedics: Machine Learning in Diagnosis of Bone Disease, Implants, and Bone Health Monitoring

open access: yesAdvanced Healthcare Materials, EarlyView.
Efficient recovery from traumatic or degenerative diseases is a great challenge, even after all the advancements in bone and cartilage regeneration. Machine learning (ML) algorithms have presented opportunities to enhance these aspects by accurately analyzing imaging data.
Maryam Kamaei   +9 more
wiley   +1 more source

Kyste hydatique du pancréas révélé par une pancréatite aigüe: à propos d'un cas

open access: yesThe Pan African Medical Journal, 2015
La localisation pancréatique du kyste hydatique est exceptionnelle, même dans les pays où la maladie hydatique sévit à l'état endémique. Nous rapportons une observation de kyste hydatique du pancréas révélée par une pancréatite aigue. Le diagnostic était
Hedfi Mohamed   +4 more
doaj   +1 more source

Oxygels: Tunable Phosphorescent Hydrogels for Cherenkov‐Excited Luminescence Imaging (CELI) of Oxygen

open access: yesAdvanced Healthcare Materials, EarlyView.
Biocompatible hydrogels with covalently embedded near‐infrared phosphorescent probes enable local tissue pO2 quantification by means of Cherenkov‐excited luminescence imaging (CELI), where optical excitation occurs within tissues upon irradiation with high‐energy electron beams.
Simin Belali   +7 more
wiley   +1 more source

Maintien de la DP malgré une fuite sous-cutanée en dialyse péritonéale : à propos d’un cas

open access: yesBulletin de la Dialyse à Domicile
(Pour lire l’article complet, en français ou anglais, cliquer sur le logo pdf à droite). La fuite sous-cutanée de dialysat représente une complication mécanique rare en dialyse péritonéale.
Sara El Maakoul   +3 more
doaj   +1 more source

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