Results 91 to 100 of about 1,825,067 (315)
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Reading Skills for Deaf Students - Scanning
, 2011 Reading skills for deaf students - scanning - introducing scanning - what is scanning - why do we scan? - how do you scan? - everyday scanning - flash videos (flv) for the deaf and hard of hearing.
Southport College, LSN, Q Projects
core
Quantitative Local Photosynthetic Flux Measurements at Isolated Chloroplasts and Thylakoid Membranes Using Scanning Electrochemical Microscopy (SECM) [PDF]
, 2013 Scanning electrochemical microscopy (SECM) offers a fast and quantitative method to measure local fluxes within photosynthesis. In particular, we have measured the flux of oxygen and ferrocyanide (Fe(CN)64–), from the artificial electron acceptor ...
Robinson, Colin +9 more
core +1 more source
Radiology Case Reports, 2015 Filariasis is an endemic infection seen in tropical and subtropical regions of the world that presents with lymphatic dysfunction in the form of lymphocoele, hydrocoele, chyluria, or groin lymphadenovarix.
Natasha N. Metha, MD +2 more
doaj +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Biomedical and biological applications of scanning electron microscopy
, 2012 Podeu consultar el llibre complet a: http://hdl.handle.net/2445/32166This article summarizes the basic principles of scanning electron microscopy and the capabilities of the technique with different examples of applications in biomedical and biological ...
Cortadellas i Raméntol, Núria +2 more
core
sfelena/TEV-6k2-mutational-scanning: TEV 6K2 deep mutational scanning
, 2022 Data used in: González R, Wu B, Li X, Martínez F, Elena SF. Mutagenesis Scanning Uncovers Evolutionary Constraints on Tobacco Etch Potyvirus Membrane-Associated 6K2 Protein. Genome Biol Evol. 2019 Apr 1;11(4):1207-1222. doi: 10.1093/gbe/evz069.
sfelena
core +1 more source
Study of a High Spectral Resolution Hyperspectral LiDAR in Vegetation Red Edge Parameters Extraction
Remote Sensing, 2019 Non-contact and active vegetation or plant parameters extraction using hyperspectral information is a prospective research direction among the remote sensing community.
Changhui Jiang +9 more
doaj +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Sensors, 2019 Here, we describe an innovative Integrated Laser Sensor (ILS) that combines four spectroscopic techniques and two vision systems into a unique, transportable device.
Violeta Lazic +7 more
doaj +1 more source