Results 71 to 80 of about 1,825,067 (315)
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Comparison of fast Fourier transform and convolution in wavelength scanning interferometry [PDF]
The assessment of surface finish has become increasingly important in the field of precision engineering. Optical interferometry has been widely used for surface measurement due to the advantages of non-contact and high accuracy interrogation.
Gao, F. +7 more
core +1 more source
Nanomotion of bacteria to determine metabolic profile
In addition to their visible motion such as swimming (e.g., with the help of flagella), bacteria can also exhibit nanomotion that is detectable only with highly sensitive instruments, and this study shows that it is possible to detect bacterial ...
S. N. Pleskova +6 more
doaj +1 more source
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Tips for the Radiologist: A nursing perspective on sedating children for CT scanning
No abstract available.
Barbara Duminiet
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Estimation of canopy structure and individual trees from laser scanning data [PDF]
During the last fifteen years, laser scanning has emerged as a data source for forest inventory. Airborne laser scanning (ALS) provides 3D data, which may be used in an automated analysis chain to estimate vegetation properties for large areas ...
Lindberg, Eva
core
Applying 3D scanning and modeling in transport design education
Advanced 3D Laser Scanning processes have developed over the last decade and are now available and affordable for medium to large companies as well as education.
Unver, Ertu +3 more
core +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source

