Results 51 to 60 of about 1,825,067 (315)
BMJ Open, 2013 Objective To describe trends in new drugs launched in the UK from 1982 to 2011 and test the hypothesis that the rate of new drug introductions has declined over the study period. There is wide concern that pharmaceutical innovation is declining. Reported
Derek J Ward +3 more
doaj +1 more source
MERGING PHOTOGRAMMETRY AND AUGMENTED REALITY: THE CANADIAN LIBRARY OF PARLIAMENT [PDF]
The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2019 In recent years, Augmented Reality (AR) technology has experienced considerable progress and the combination of AR and 3D modeling opens up new opportunities regarding 3D data visualization and interaction.
B. Carrión-Ruiz +4 more
doaj +1 more source
Вестник Дагестанского государственного технического университета: Технические науки, 2022 Objective. The article discusses hardware and software methods of protecting the resources of the personal data information system from unauthorized access by means of "sniffing attacks"; the essence of which is to intercept data that is delivered within
A. R. Gazizov
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
To Scan or Not to Scan, That is the Question
Annals of Colorectal Research, 2014 Background Selective conservative management of abdominal penetrating trauma can significantly minimize the morbidity and length of hospitalization by decreasing the rate of unnecessary laparotomies. Objectives In the present study, we reported the outcome of newest guidelines of our trauma center in one year. Patients and Methods All patients
Sepideh Sefidbakht, Fariba Zarei
openaire +1 more source
SIRIS: a high resolution scanning infrared camera for examining paintings [PDF]
, 2005 The new SIRIS (Scanning InfraRed Imaging System) camera developed at the National Gallery in London allows highresolution images of paintings to be made in the near infrared region (900–1700 nm).
Richard Bingham +11 more
core +1 more source
Measuring Leaf Water Content with Dual-Wavelength Intensity Data from Terrestrial Laser Scanners
Remote Sensing, 2016 Decreased leaf moisture content, typically measured as equivalent water thickness (EWT), is an early signal of tree stress caused by drought, disease, or pest insects.
Samuli Junttila +8 more
doaj +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source