Results 61 to 70 of about 2,385,614 (399)

Volume electron microscopy

open access: yesNature Reviews Methods Primers, 2022
Life exists in three dimensions, but until the turn of the century most electron microscopy methods provided only 2D image data. Recently, electron microscopy techniques capable of delving deep into the structure of cells and tissues have emerged ...
C. Peddie   +13 more
semanticscholar   +1 more source

Combined scanning force microscopy and scanning tunneling spectroscopy of an electronic nano-circuit at very low temperature [PDF]

open access: yesApplied Physics Letters 90 (22/01/2007) 043114, 2006
We demonstrate the combination of scanning force microscopy and scanning tunneling spectroscopy in a local probe microscope operating at very low temperature (60 mK). This local probe uses a quartz tuning fork ensuring high tunnel junction stability. We performed the spatially-resolved spectroscopic study of a superconducting nano-circuit patterned on ...
arxiv   +1 more source

New immunolatex spheres: visual markers of antigens on lymphocytes for scanning electron microscopy [PDF]

open access: yes, 1975
New immunochemical reagents consisting of antibodies bound to small latex spheres were used as visual markers for the detection and localization of cell surface antigens by scanning electron microscopy.
Dreyer, William J.   +3 more
core   +2 more sources

3D correlative light and electron microscopy of cultured cells using serial blockface scanning electron microscopy

open access: yesJournal of Cell Science, 2017
The processes of life take place in multiple dimensions, but imaging these processes in even three dimensions is challenging. Here, we describe a workflow for 3D correlative light and electron microscopy (CLEM) of cell monolayers using fluorescence ...
M. Russell   +14 more
semanticscholar   +1 more source

Electron counting detectors in scanning transmission electron microscopy via hardware signal processing

open access: yesNature Communications, 2023
Transmission electron microscopy is a pivotal instrument in materials and biological sciences due to its ability to provide local structural and spectroscopic information on a wide range of materials.
Jonathan J. P. Peters   +6 more
doaj   +1 more source

Imaging of double slit interference by scanning gate microscopy [PDF]

open access: yes, 2014
We consider scanning gate microscopy imaging of the double slit interference for a pair of quantum point contacts (QPCs) defined within the two-dimensional electron gas. The interference is clearly present in the scattered electron wave functions for each of the incident subbands.
arxiv   +1 more source

Integrative analysis of circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients: a comprehensive approach

open access: yesMolecular Oncology, EarlyView.
This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou   +13 more
wiley   +1 more source

AEcroscoPy: A software-hardware framework empowering microscopy toward automated and autonomous experimentation [PDF]

open access: yesarXiv, 2023
Microscopy, in particular scanning probe and electron microscopy, has been pivotal in improving our understanding of structure-function relationships at the nanoscale and is by now ubiquitous in most research characterization labs and facilities. However, traditional microscopy operations are still limited largely by a human-centric click-and-go ...
arxiv  

High Dynamic Range Pixel Array Detector for Scanning Transmission Electron Microscopy [PDF]

open access: yesMicroscopy and Microanalysis, 2015
We describe a hybrid pixel array detector (electron microscope pixel array detector, or EMPAD) adapted for use in electron microscope applications, especially as a universal detector for scanning transmission electron microscopy.
M. Tate   +15 more
semanticscholar   +1 more source

Mapping Hsp104 interactions using cross‐linking mass spectrometry

open access: yesFEBS Open Bio, EarlyView.
This study examines how cross‐linking mass spectrometry can be utilized to analyze ATP‐induced conformational changes in Hsp104 and its interactions with substrates. We developed an analytical pipeline to distinguish between intra‐ and inter‐subunit contacts within the hexameric homo‐oligomer and discovered contacts between Hsp104 and a selected ...
Kinga Westphal   +3 more
wiley   +1 more source

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