Results 111 to 120 of about 288,228 (303)

Topically Delivered Treg‐Attracting Microparticle‐Hydrogel Composites Recruit Regulatory T Cells and Limit Cardiac Injury After Severe Ischemia

Advanced Healthcare Materials, EarlyView.
CCL22‐releasing PLGA microparticles (MP) suspended in topically applied hydrogels (HEART) establish a sustained chemokine gradient at the injured myocardium. HEART recruits CCR4+ regulatory T cells, reduces infarct size and graft fibrosis, and improves cardiac function.
Matthew A. Borrelli, Alexis T. Reese, Jordan J. P. Warunek, Betsy Ann Varghese, Canxing Lin, Jeffery J. Baust, Brenda McMahon, Steven R. Little, Hēth R. Turnquist   +8 more
wiley   +1 more source

Laser‐Assisted Phase Engineering of 2D MoS2 for Efficient Solution‐Processed Electronics

Advanced Materials, EarlyView.
Here, local laser‐assisted phase transition from solution‐processed phase‐pure 1T′ to 2H MoS2 is shown to critically depend on the irradiation atmosphere. While processing in air leads to damaged insulating regions, inert conditions yield semiconducting 2H domains, enabling direct field‐effect transistor patterning with optimized lateral 1T′‐2H MoS2 ...
Anna Zhuravlova, Minjuan Li, Osamah Alharbi, Yeonsu Jeong, Bin Han, Lei Gao, Mischa Bonn, Mario Lanza, Sheng Yang, Antonio Gaetano Ricciardulli, Paolo Samorì   +10 more
wiley   +1 more source

Can parents reliably report burn scar quality on behalf of their child? A clinimetric observational study of child-proxy agreement on the pediatric patient scale of the POSAS

Journal of Patient-Reported Outcomes
Background The assessment of scar quality is an essential component of follow-up care and outcome evaluation in pediatric burn patients. The pediatric patient scale of the Patient and Observer Scar Assessment Scale (POSAS) is a recently developed patient-
Frederique M. Kemme, Mieke Anthonissen, Annebeth Meij-de Vries, Pien Lelifeld, Thibau Demarbaix, Paul P. M. van Zuijlen, Anouk Pijpe   +6 more
doaj   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Scar sarcoidosis - Sparing Post surgical Scar

, 1998
Infiltration of old scars by sarcoidal granuloma is not uncommon. However, pathogenesis of scar sarcoid is not clear. Peculiar involvement of road traffic accident scars with sparing of postoperative scar by granulomatous infiltrate in our patient ...
Sharma VK, Handa S, Mitali G, Muralidhar S, Kumar B   +4 more
core  

Fabrication of Aligned Polycaprolactone Nanofibrillar Bundles to Control Cell‐Mediated Collagen Deposition in Engineered Cartilage

Advanced Materials, EarlyView.
Melt electrofibrillation (MEF) enables the fabrication of nanofibrillar PCL scaffolds with defined architectures that guide cellular alignment and retention during cartilage tissue engineering. Unlike conventional melt electrowriting, MEF consistently directs collagen type II‐rich extracellular matrix organization, providing a tunable platform to ...
Alba Pueyo Moliner, Lennard Spauwen, James L. Martin Robinson, Ángela García Grech, Isabelle Martinier, Sara Grasselli, Aylin Kara Özenler, Matthias Ryma, Jürgen Groll, Mylène de Ruijter, Jos Malda   +10 more
wiley   +1 more source

Cellular heterogeneity in hypertrophic burn scars in response to carbon dioxide laser therapy

Communications Medicine
Background Ablative fractional carbon dioxide (AFCO2) laser therapy is used for treating pathological scarring. However, mechanisms underlying reduction in hypertrophic scarring are poorly understood.
Yung-Yi Chen, Christopher Mahony, Jason Turner, Charlotte G. Smith, Abdulrazak Abdulsalam, Ezekwe Amirize, Amberley Prince, Adrian Heagerty, Claudia Roberts, Adam Croft, Yvonne Wilson, Naiem Moiemen, Janet M. Lord   +12 more
doaj   +1 more source

Mechanoactive Biomaterials for Cell–Matrix Mechanotransduction

Advanced Materials, EarlyView.
The graphical abstract shows how individual triggers (force, light, or temperature) and combined optothermal or receptor‐targeted actuation induce material responses at the tissue, cellular, and receptor scales. Their spatial (global or focused) and temporal (continuous or cyclic) modulation determines the resulting mechanical output.
Yi‐Tung Lu, Alison E. John, Marc A. Fernández‐Yagüe   +2 more
wiley   +1 more source

Programmable Microgel Degradation in Dynamic Granular Hydrogels Guides Extracellular Matrix Assembly During Tissue Repair

Advanced Materials, EarlyView.
This study reports on the chemical modification of hyaluronic acid to create hydrogels with hydrolytic degradability ranging from 2–28 days. Granular hydrogels that undergo timed degradation to increase porosity enhance cell invasion and provisional ECM remodeling in a muscle injury model, leading to reduced fibrosis and improved regeneration ...
Zhiyuan Chen, Tuba Marjan, Xinyue Lu, Nicole E. Mertens, Keira Vesy, Dean E. Stornello, James F. Markworth, Taimoor H. Qazi   +7 more
wiley   +1 more source

Mastectomy Scar Healing: A Comparative Analysis of Fibrin Sealant and Quilting Techniques Using the Hollander Wound Evaluation Scale

Nigerian Journal of Medicine
Introduction: Surgical scars represent both a cosmetic concern and an unavoidable surgical outcome. For patients, particularly those who have undergone a mastectomy, the scar serves as the primary external reminder of a significant medical experience ...
Ibrahim Umar Abubakar, Bello Muhammed Bashir, Fahd Yahaya Hassan, Nazish Perveen Aquil, J. Ndas Legbo, Moyijo Abubakar Maishanu, Mikail Abdullahi   +6 more
doaj   +1 more source