Results 51 to 60 of about 11,215 (268)

Scarring Alopecia and the PPAR-γ Connection [PDF]

Journal of Investigative Dermatology, 2009
The pathobiology of primary cicatricial ("scarring") alopecia (PCA) remains poorly understood and underinvestigated. In this issue, Karnik et al. identify a previously unsuspected player, peroxisome proliferator-activated receptor-gamma (PPARgamma), in the pathogenesis of the most frequent form of PCA, lichen planopilaris (LPP).
Ralf Paus, Ralf Paus, Matthew Harries
openaire   +3 more sources

PPAR? Downregulation by TGF in Fibroblast and Impaired Expression and Function in Systemic Sclerosis: A Novel Mechanism for Progressive Fibrogenesis [PDF]

, 2010
The nuclear orphan receptor peroxisome proliferator-activated receptor-gamma (PPAR-γ) is expressed in multiple cell types in addition to adipocytes. Upon its activation by natural ligands such as fatty acids and eicosanoids, or by synthetic agonists such
A Galli, A Kis, A Milano, AK Ghosh, AK Ghosh, AK Ghosh, AK Ghosh, Asish K. Ghosh, BC Willis, BM Psaty, C Beyer, C Dong, Carol Feghali-Bostwick, DA Culver, ED Rosen, ED Rosen, F Verrecchia, F Zheng, G Lakos, H Ha, HA Burgess, J Berger, J Varga, J Varga, JE Milam, Jennifer L. Sargent, JL Sargent, John Varga, Joy Sturtevant, JT Tan, Jun Wei, KA Longo, Kazuhiro Komura, KM Hong, L Fajas, L Yang, LS Higgins, M Dudas, M Kapoor, M Kapoor, M Lehrke, M Trojanowska, M Wu, Manu Jain, MF Simon, Michael L. Whitfield, Minghua Wu, OA Gressner, P Karnik, P Tontonoz, Qi-Quan Huang, R Fleischmajer, S Dennler, S Kim, S Sonnylal, S Zheng, SE Ross, SH Liu, SJ Chen, SZ Duan, T Kawai, T Miyahara, T Shiomi, TM McIntyre, V Zoete, W Yuan, X Li, X Liu, X Shi-wen, X Tan, Y Mori, Y Mori, Y Park, Y Shi, Y Wang, Z Yun   +75 more
core   +4 more sources

Scarring alopecia in psoriasis.

Acta Dermato-Venereologica, 1990
Scalp biopsies were taken from 3 patients with a scarring alopecia associated with severe scalp psoriasis. The histological findings in each case showed inflammatory destruction of the infundibular region of the hair follicle. The similarity of these changes in each case strongly suggests an association with the psoriasis.
A L, Wright, A G, Messenger
openaire   +2 more sources

Erosive pustular dermatosis of the scalp successfully treated with oral prednisone and topical tacrolimus [PDF]

Anais Brasileiros de Dermatologia, 2013
Erosive pustular dermatosis of the scalp is a rare inflammatory disorder of the scalp, affecting elderly patients after local trauma and leading to scarring or cicatricial alopecia. Case Report: An elderly female patient complained of painful pustules on
Mariana Ribas Zahdi, Gabriela Bestani Seidel, Vanessa Cristina Soares, Camila Fernanda Novak Pinheiro de Freitas, Fabiane Andrade Mulinari-Brenner   +4 more
doaj   +1 more source

Clinical recognition and management of alopecia in women of color,

International Journal of Women's Dermatology, 2019
Certain types of alopecia, such as traction alopecia, discoid lupus erythematosus, and central centrifugal cicatricial alopecia, occur more commonly in African-American individuals than in those of other ethnicities.
Jodie Raffi, BA, Raagini Suresh, BS, Oma Agbai, MD, FAAD   +2 more
doaj   +1 more source

Tufted Hair Folliculitis: A Case Report [PDF]

, 2013
Tufted hair folliculitis (THF) is a recurrent and progressive folliculitis of the scalp that resolves with irregular areas of scarring alopecia within which numerous hair tufts emerge from dilated follicular openings.
Alev Eken, İlknur Balta, Meral Ekşioğlu, Murat Baykır, Murat Baykır, Müzeyyen Astarcı, Şahande Nur Yüksel   +6 more
core   +1 more source

A 61-year-old Filipino man with lichen planus concomitant with cicatricial alopecia, mimicking discoid lupus erythematosus [PDF]

, 2023
Background: Lichen planus (LP) is an idiopathic inflammatory disease affecting the skin, mucous membranes, hair, and nails. Even though rare, LP may also present as cicatricial alopecia or a condition referred to as lichen planopilaris (LPP).
Carpio, Benedicto dL, Guzman, Amelita Tanglao-De, Harris, Lie Michelle E., Lapitan-Torres, Armelia, Regalado-Morales, Eileen   +4 more
core   +2 more sources

A randomized, placebo‐controlled trial of hydroxychloroquine in incomplete lupus

Arthritis &Rheumatology, Accepted Article.
Objectives Patients with features of systemic lupus erythematosus (SLE) who do not fulfill classification criteria can be designated as incomplete lupus (ILE). This condition includes individuals with a high risk of progression to SLE. Treatment of ILE may reduce symptoms, severity and incidence of SLE. Methods Hydroxychloroquine (HCQ) was chosen as an
Nancy J. Olsen, Duanping Liao, Judith A. James, Joel M. Guthridge, Cristina Arriens, Diane Kamen, Mariko Ishimori, Daniel J. Wallace, Christopher Striebich, Sonali Narain, Benjamin F. Chong, Fan He, Eric W. Schaefer, Vernon M. Chinchilli, David R. Karp   +14 more
wiley   +1 more source

Alopecia neoplastica inducing underlying lytic skull metastasis

Indian Journal of Dermatology, 2022
Alopecia neoplastica is a rare type of cutaneous metastasis. The most frequent presentation consists of red-violaceous nodular scarring alopecia located at the parietal area.
Rubén Linares Navarro, Héctor Perandones González, Pedro Sánchez Sambucety, Ana De La Hera Magallanes, Manuel Ángel Rodríguez Prieto   +4 more
doaj   +1 more source

Canine recurrent flank alopecia: a synthesis of theory and practice [PDF]

, 2014
Canine recurrent flank alopecia is a non-inflammatory, non-scarring alopecia of unknown etiology and has a visually striking clinical presentation.
Daminet, Sylvie, De Cock, Hilde, Declercq, Jan, Vandenabeele, Sophie   +3 more
core   +2 more sources