Results 41 to 50 of about 687,411 (298)
FEBS Letters, EarlyView.This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao +7 more
wiley +1 more source
Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice
FEBS Letters, EarlyView.In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász +6 more
wiley +1 more source
Quantum wake dynamics in Heisenberg antiferromagnetic chains
Nature Communications, 2022 It has long been suggested that the inverse Fourier transform of neutron scattering data gives access to space- and time-resolved spin-spin correlations. Scheie et al.
A. Scheie +6 more
doaj +1 more source
Functional role and folding properties of the glucan‐binding domain of oral bacterial glucansucrase
FEBS Letters, EarlyView.The role of the glucan‐binding domain in Streptococcus sobrinus glucansucrase was examined, focusing on its impact on enzymatic activity, dextran binding, and structural stability of deletion mutants and a circularly permuted protein. Our research revealed that glucosyl transfer efficiency is linked to cooperative interdomain folding.
Hideyuki Komatsu +5 more
wiley +1 more source
, 2021 The present chapter reviews current neutron and x-ray scattering techniques employed to elucidate the magnetic structures and spin dynamics of magnetic materials. Both techniques provide measurements as a function of the energy and the momentum transferred from the spin system to the probe particles, in terms of five-dimensional data sets as a function
Jeffrey W. Lynn, Bernhard Keimer
openaire +3 more sources
Development of visible light‐sensitive human neuropsin (OPN5) via single amino acid substitution
FEBS Letters, EarlyView.The present study determines a key amino acid residue, Lys91, for defining UV sensitivity of human OPN5. Heterologous action spectroscopy of the wild type and K91 mutants of OPN5 in HEK293T cells reveals that substitution of Lys91 with neutral (alanine) or acidic amino acids (glutamic or aspartic acids) causes substantial shifts in spectral sensitivity
Yusuke Sakai +2 more
wiley +1 more source
Efficient Simulation Method for High Quality SAR Images of Complex Ground Vehicles
Leida xuebao, 2015 Aiming at meeting the requirement of the amass high-quality SAR images needed by template-based ground target recognition engineering practice, a novel efficient SAR signal level simulation method is proposed.
Dong Chun-zhu +3 more
doaj
IEEE Access, 2022 In this paper, we employed an efficient polarization conversion metasurface (PCM) to achieve broadband radar cross section (RCS) reduction for plane targets.
Zhongru Ren +5 more
doaj +1 more source
FEBS Letters, EarlyView.Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile +8 more
wiley +1 more source
International Journal of Antennas and Propagation, 2019 In previous studies, the trapped surface wave, which is defined by the residue sums, has been addressed in the evaluation of the Sommerfeld integrals describing electromagnetic field of a vertical dipole in the presence of three-layered or four-layered ...
Hong Lei Xu +5 more
doaj +1 more source